In the fruit fly Drosophila, a rudimentary wing called 'vestigial' and dark body color called 'ebony' are inherited as independently assorting genes and are recessive to their dominant counterparts full wing and gray body color. Dihybrid dominant-phenotype males and females are crossed, and 3200 progeny are produced. How many progeny flies are expected to be found in each phenotypic class?
Table of contents
- 1. Introduction to Genetics51m
- 2. Mendel's Laws of Inheritance3h 37m
- 3. Extensions to Mendelian Inheritance2h 41m
- 4. Genetic Mapping and Linkage2h 28m
- 5. Genetics of Bacteria and Viruses1h 21m
- 6. Chromosomal Variation1h 48m
- 7. DNA and Chromosome Structure56m
- 8. DNA Replication1h 10m
- 9. Mitosis and Meiosis1h 34m
- 10. Transcription1h 0m
- 11. Translation58m
- 12. Gene Regulation in Prokaryotes1h 19m
- 13. Gene Regulation in Eukaryotes44m
- 14. Genetic Control of Development44m
- 15. Genomes and Genomics1h 50m
- 16. Transposable Elements47m
- 17. Mutation, Repair, and Recombination1h 6m
- 18. Molecular Genetic Tools19m
- 19. Cancer Genetics29m
- 20. Quantitative Genetics1h 26m
- 21. Population Genetics50m
- 22. Evolutionary Genetics29m
2. Mendel's Laws of Inheritance
Monohybrid Cross
Problem 38
Textbook Question
Sweet yellow tomatoes with a pear shape bring a high price per basket to growers. Pear shape, yellow color, and terminal flower position are recessive traits produced by alleles f, r, and t, respectively. The dominant phenotypes for each trait—full shape, red color, and axial flower position—are the product of dominant alleles F, R, and T. A farmer has two pure-breeding tomato lines. One is full, yellow, terminal and the other is pear, red, axial. Design a breeding experiment that will produce a line of tomato that is pure-breeding for pear shape, yellow color, and axial flower position.

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Step 1: Identify the genotypes of the two pure-breeding tomato lines. Since one line is full, yellow, and terminal, its genotype is FFrrtt (homozygous dominant for shape, homozygous recessive for color, and homozygous recessive for flower position). The other line, which is pear, red, and axial, has the genotype ffRRtt (homozygous recessive for shape, homozygous dominant for color, and homozygous dominant for flower position).
Step 2: Perform a cross between the two pure-breeding lines. The F1 generation will inherit one allele from each parent for each gene. This results in the genotype FfRrtt for all F1 individuals, which are heterozygous for shape and color, and homozygous recessive for flower position. The phenotype of the F1 generation will be full, red, and terminal.
Step 3: To produce a line that is pure-breeding for pear shape, yellow color, and axial flower position (ffrrTT), perform a self-cross of the F1 generation (FfRrtt × FfRrtt). This will allow for independent assortment and recombination of alleles for all three traits.
Step 4: Use a Punnett square or probability rules to determine the genotypic ratios in the F2 generation. For each gene, calculate the probability of obtaining the desired homozygous recessive genotype (ff for shape, rr for color) and homozygous dominant genotype (TT for flower position). Combine these probabilities to identify the proportion of offspring with the desired genotype ffrrTT.
Step 5: Screen the F2 generation for individuals with the desired phenotype (pear shape, yellow color, and axial flower position). Confirm their genotype through test crosses or molecular techniques if necessary. Select these individuals and propagate them to establish a pure-breeding line with the desired traits.

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Key Concepts
Here are the essential concepts you must grasp in order to answer the question correctly.
Mendelian Genetics
Mendelian genetics is the study of how traits are inherited through generations based on the principles established by Gregor Mendel. It involves understanding dominant and recessive alleles, where dominant traits mask the expression of recessive ones. This framework is essential for predicting the outcomes of genetic crosses, such as those involving the traits of the tomatoes in the question.
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Descriptive Genetics
Genotype and Phenotype
The genotype refers to the genetic makeup of an organism, while the phenotype is the observable physical or biochemical characteristics resulting from the genotype. In the context of the tomato breeding experiment, understanding the genotypes of the parent plants (pure-breeding for specific traits) is crucial for predicting the phenotypes of the offspring and ensuring the desired traits are expressed.
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Punnett Square
A Punnett square is a diagram used to predict the genetic outcomes of a cross between two organisms. It allows for the visualization of how alleles from each parent combine to form the genotypes of the offspring. In this breeding experiment, a Punnett square can help determine the likelihood of producing pure-breeding lines for the desired recessive traits of pear shape, yellow color, and axial flower position.
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Chi Square Analysis
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