In humans, the ABO blood type is under the control of autosomal multiple alleles. Color blindness is a recessive X-linked trait. If two parents who are both type A and have normal vision produce a son who is color-blind and is type O, what is the probability that their next child will be a female who has normal vision and is type O?

A husband and wife have normal vision, although both of their fathers are red–green color-blind, an inherited X-linked recessive condition. What is the probability that their first child will be (a) a normal son, (b) a normal daughter, (c) a color-blind son, (d) a color-blind daughter?

In fruit flies, yellow body (y) is recessive to gray body , and the trait of body color is inherited on the X chromosome. Vestigial wing (v) is recessive to full-sized wing (v⁺), and the trait has autosomal inheritance. A cross of a male with yellow body and full wings to a female with gray body and full wings is made. Based on an analysis of the progeny of the cross shown below, determine the genotypes of parental and progeny flies.

[Table below appears at this point containing crosses and results]

In a species of fish, a black spot on the dorsal fin is observed in males and females. A fish breeder carries out a pair of reciprocal crosses and observes the following results.

Identify which sex is heterogametic. Give genotypes for the parents in each cross, and explain the progeny proportions in each cross.

In a species of fish, a black spot on the dorsal fin is observed in males and females. A fish breeder carries out a pair of reciprocal crosses and observes the following results.

Why does this evidence support the hypothesis that a black spot is sex linked?

Lesch–Nyhan syndrome (OMIM 300322) is a rare X-linked recessive disorder that produces severe mental retardation, spastic cerebral palsy, and self-mutilation.

What is the probability that the first son of a man whose brother has Lesch–Nyhan syndrome will be affected?

Lesch–Nyhan syndrome (OMIM 300322) is a rare X-linked recessive disorder that produces severe mental retardation, spastic cerebral palsy, and self-mutilation.

If the first son of the woman described in (a) is affected, what is the probability that her second son is affected?

Lesch–Nyhan syndrome (OMIM 300322) is a rare X-linked recessive disorder that produces severe mental retardation, spastic cerebral palsy, and self-mutilation.

What is the probability that the first son of a woman whose brother has Lesch–Nyhan syndrome will be affected?

In Drosophila, an X-linked recessive mutation, scalloped (sd), causes irregular wing margins. Diagram the F₁ and F₂ results if (a) a scalloped female is crossed with a normal male; (b) a scalloped male is crossed with a normal female. Compare these results with those that would be obtained if the scalloped gene were autosomal.