The diagram below shows a DNA duplex. The template strand is i...

Question

The diagram below shows a DNA duplex. The template strand is identified, as is the location of the nucleotide. consensus sequences.

Assume this region contains a gene transcribed to form mRNA in a eukaryote. Identify the location of the most common promoter.

Accepted Answer

Hey, everyone. Let's take a look at this question together. An experimental study is carried out at Stanford University to understand the transcription of a rare gene involved in neurofibromatosis. Which one of the following is the most common promoter consensus sequence involved in the transcription of DNA in eukaryotes. Is it answer choice? A the 10 box also known as the prib no box, which is a sequence of six nucleotide located 10 base pairs upstream of the transcription start site. Answer choice B the 35 box which is located 35 base pairs upstream of the transcription start site and has a consensus sequence of TT G AC A answer choice C the T A T A box, which is a sequence of four nucleotides located approximately 25 to 30 base pairs upstream of the transcription start site or answer choice D enhancer elements which are important in regulating gene expression in eukaryotes. Let's work this problem out together to try to figure out which of the following answer choices is the most common promoter consensus sequence involved in the transcription of D N A&E Caros. So based on our answer choices, we are trying to determine which of the following is the most common promoter consensus sequence involved in the transcription of DNA in eukaryotes. And so we have the 10 box, also known as the prib no box. We have the 35 box, the T A T A box or enhancer elements and of the answer choices that we have the 10 box or the prib no box and the 35 box are actually found in pro Caros and they are not commonly found in you Caro. And since we're trying to figure out that most common promoter sequence involved in the transcription of DNA in U Caros, we can go ahead and eliminate answer choice A and answer choice. B since those are both promoter elements found in pro Caros and are not as commonly found in U carry odes. And now we have to decide between answer choice C the T A T A box or answer choice D enhancer elements, which those enhancer elements are important in regulating gene expression in eukaryotes since they are regulatory elements and not a promoter consensus sequence, which means we can go ahead and eliminate answer choice D and select answer choice C the T A T A box as the correct answer. Since answer choice C, the T A T A box, which is a sequence of four nucleotides T A T A located approximately 25 to 30 base pairs upstream of the transcription start site is the most common promoter consensus sequence involved in the transcription of DNA in New Caros. So this is the most common promoter consensus sequence, making answer choice C the correct answer since we know that the 10 box and the 35 box are found in pro Caros and are not common in E Caros allowing us to eliminate answer choices A and B and answer choice. D enhancer elements are not a promoter, consensus sequence and enhancer elements are regulatory elements which while important in regulating gene expression in eukaryotes, they are not promoter consensus sequences. So answer choice D can also be eliminated, leaving us with answer choice C as the only correct answer here since the T A T A box is the most common promoter consensus sequence involved in the transcription of DNA and eukaryotes. I hope you found this video to be helpful. Thank you and goodbye.

The diagram below shows a DNA duplex. The template strand is identified, as is the location of the nucleotide. consensus sequences.

Assume this region contains a gene transcribed to form mRNA in a eukaryote. Identify the location of the most common promoter.

Key Concepts

DNA Structure

Promoter Regions

Transcription in Eukaryotes

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