Identify two differences in chemical composition that distinguish DNA from RNA.
Table of contents
- 1. Introduction to Genetics51m
- 2. Mendel's Laws of Inheritance3h 37m
- 3. Extensions to Mendelian Inheritance2h 41m
- 4. Genetic Mapping and Linkage2h 28m
- 5. Genetics of Bacteria and Viruses1h 21m
- 6. Chromosomal Variation1h 48m
- 7. DNA and Chromosome Structure56m
- 8. DNA Replication1h 10m
- 9. Mitosis and Meiosis1h 34m
- 10. Transcription1h 0m
- 11. Translation58m
- 12. Gene Regulation in Prokaryotes1h 19m
- 13. Gene Regulation in Eukaryotes44m
- 14. Genetic Control of Development44m
- 15. Genomes and Genomics1h 50m
- 16. Transposable Elements47m
- 17. Mutation, Repair, and Recombination1h 6m
- 18. Molecular Genetic Tools19m
- 19. Cancer Genetics29m
- 20. Quantitative Genetics1h 26m
- 21. Population Genetics50m
- 22. Evolutionary Genetics29m
1. Introduction to Genetics
Fundamentals of Genetics
Problem 23
Textbook Question
Fill in the missing nucleotides (so there are three per block) and the missing amino acid abbreviations in the graphic shown here.


1
Identify the missing nucleotides in the DNA template strand by using the complementary base-pairing rules. For DNA, adenine (A) pairs with thymine (T), and cytosine (C) pairs with guanine (G). Fill in the missing nucleotides in the template strand based on the coding strand provided.
Transcribe the DNA template strand into mRNA. Use the base-pairing rules for transcription: adenine (A) in DNA pairs with uracil (U) in RNA, thymine (T) in DNA pairs with adenine (A) in RNA, and cytosine (C) pairs with guanine (G). Fill in the missing mRNA codons.
Determine the tRNA anticodons that correspond to the mRNA codons. Remember that tRNA anticodons are complementary to the mRNA codons, following the base-pairing rules (A pairs with U, and C pairs with G). Fill in the missing tRNA anticodons.
Use the genetic code table to translate the mRNA codons into their corresponding amino acids. Each codon specifies one amino acid. Fill in the missing amino acid abbreviations (both 3-letter and 1-letter codes).
Double-check your work to ensure that the DNA, mRNA, tRNA, and amino acid sequences are consistent with each other and follow the rules of transcription and translation.

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Key Concepts
Here are the essential concepts you must grasp in order to answer the question correctly.
DNA Structure and Function
DNA consists of two strands forming a double helix, with each strand made up of nucleotides. The coding strand contains the sequence that is transcribed into mRNA, while the template strand serves as a guide for RNA polymerase during transcription. Understanding the directionality (5' to 3') of these strands is crucial for accurately filling in missing nucleotides.
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DNA Structure
Transcription and mRNA
Transcription is the process by which the genetic information in DNA is copied into mRNA. The mRNA codons are sequences of three nucleotides that correspond to specific amino acids. Recognizing how codons are formed from the DNA template is essential for completing the missing sequences in the question.
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Prokaryotic Transcription
tRNA and Translation
Transfer RNA (tRNA) molecules carry amino acids to the ribosome during translation, matching their anticodons with the mRNA codons. Each tRNA anticodon is complementary to a specific mRNA codon, ensuring the correct amino acid is added to the growing polypeptide chain. Understanding this relationship is key to determining the correct amino acid abbreviations in the graphic.
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Translation initiation
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