The cell cycle operates in the same way in all eukaryotes, from single-celled yeast to humans, and all share numerous genes whose functions are essential for the normal progression of the cycle. Discuss why you think this is the case.
Table of contents
- 1. Introduction to Genetics51m
- 2. Mendel's Laws of Inheritance3h 37m
- 3. Extensions to Mendelian Inheritance2h 41m
- 4. Genetic Mapping and Linkage2h 28m
- 5. Genetics of Bacteria and Viruses1h 21m
- 6. Chromosomal Variation1h 48m
- 7. DNA and Chromosome Structure56m
- 8. DNA Replication1h 10m
- 9. Mitosis and Meiosis1h 34m
- 10. Transcription1h 0m
- 11. Translation58m
- 12. Gene Regulation in Prokaryotes1h 19m
- 13. Gene Regulation in Eukaryotes44m
- 14. Genetic Control of Development44m
- 15. Genomes and Genomics1h 50m
- 16. Transposable Elements47m
- 17. Mutation, Repair, and Recombination1h 6m
- 18. Molecular Genetic Tools19m
- 19. Cancer Genetics29m
- 20. Quantitative Genetics1h 26m
- 21. Population Genetics50m
- 22. Evolutionary Genetics29m
9. Mitosis and Meiosis
Mitosis
Problem 32l
Textbook Question
From a piece of blank paper, cut out three sets of four cigar-shaped structures (a total of 12 structures). These will represent chromatids. Be sure each member of a set of four chromatids has the same length and girth. In set one, label two chromatids 'A' and two chromatids 'a.' Cut each of these chromatids about halfway across near their midpoint and slide the two 'A' chromatids together at the cuts to form a single set of attached sister chromatids. Do the same for the 'a' chromatids. In the second set of four chromatids, label two 'B' and two 'b.' Cut and slide these together as you did for the first set, joining the 'B' chromatids together and the 'b' chromatids together. Repeat this process for the third set of chromatids, labeling them as 'D' and 'd.' You now have models for three pairs of homologous chromosomes, for a total of six chromosomes. What are the genotypes of the daughter cells?

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Step 1: Understand the concept of homologous chromosomes and sister chromatids. Homologous chromosomes are pairs of chromosomes, one inherited from each parent, that have the same genes but may have different alleles. Sister chromatids are identical copies of a single chromosome, formed during DNA replication.
Step 2: Recognize that the labeling ('A' and 'a', 'B' and 'b', 'D' and 'd') represents alleles of genes on homologous chromosomes. 'A' and 'a' are alleles for one gene, 'B' and 'b' for another, and 'D' and 'd' for a third gene.
Step 3: Note that the process described involves creating models of homologous chromosomes by pairing sister chromatids ('A' with 'A', 'a' with 'a', etc.) and grouping homologous pairs ('A/a', 'B/b', 'D/d'). This setup represents the chromosomes before cell division.
Step 4: Consider the type of cell division that will occur. If this is mitosis, the daughter cells will receive identical sets of chromosomes, maintaining the same genotype as the parent cell. If this is meiosis, homologous chromosomes will separate during meiosis I, and sister chromatids will separate during meiosis II, leading to daughter cells with different combinations of alleles.
Step 5: To determine the genotypes of the daughter cells, analyze the segregation of alleles during meiosis. For example, if the parent cell is heterozygous for all three genes (AaBbDd), the daughter cells could have combinations such as ABD, AbD, aBD, or abD, depending on how the alleles segregate during meiosis.

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Key Concepts
Here are the essential concepts you must grasp in order to answer the question correctly.
Chromatids and Chromosomes
Chromatids are the two identical halves of a replicated chromosome, joined together at a region called the centromere. During cell division, specifically in meiosis, these chromatids separate to ensure that each daughter cell receives the correct number of chromosomes. Understanding the structure and behavior of chromatids is essential for predicting the genetic makeup of daughter cells.
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Chromatin
Homologous Chromosomes
Homologous chromosomes are pairs of chromosomes that have the same structure and gene sequence but may carry different alleles. In the context of the question, the sets labeled 'A', 'a', 'B', 'b', 'D', and 'd' represent different alleles of the same genes on homologous chromosomes. This concept is crucial for determining the genotypes of daughter cells after meiosis, as it influences genetic variation.
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Chromosome Structure
Genotype and Alleles
A genotype refers to the genetic constitution of an organism, specifically the alleles present for a given gene. In this scenario, the daughter cells will inherit combinations of the alleles from the parent chromatids, leading to various genotypes. Understanding how alleles combine during cell division is key to predicting the genetic outcomes in the daughter cells.
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