Suppose you want to develop a population of Drosophila that would rapidly learn to avoid certain substances the flies could detect by smell. Based on the heritability estimate you obtained in Problem 16, do you think it would be worth doing this by artificial selection? Why or why not?
Table of contents
- 1. Introduction to Genetics51m
- 2. Mendel's Laws of Inheritance3h 37m
- 3. Extensions to Mendelian Inheritance2h 41m
- 4. Genetic Mapping and Linkage2h 28m
- 5. Genetics of Bacteria and Viruses1h 21m
- 6. Chromosomal Variation1h 48m
- 7. DNA and Chromosome Structure56m
- 8. DNA Replication1h 10m
- 9. Mitosis and Meiosis1h 34m
- 10. Transcription1h 0m
- 11. Translation58m
- 12. Gene Regulation in Prokaryotes1h 19m
- 13. Gene Regulation in Eukaryotes44m
- 14. Genetic Control of Development44m
- 15. Genomes and Genomics1h 50m
- 16. Transposable Elements47m
- 17. Mutation, Repair, and Recombination1h 6m
- 18. Molecular Genetic Tools19m
- 19. Cancer Genetics29m
- 20. Quantitative Genetics1h 26m
- 21. Population Genetics50m
- 22. Evolutionary Genetics29m
20. Quantitative Genetics
Heritability
Problem 19
Textbook Question
During a visit, your grandparents comment on how tall you are compared with them. You tell them that in your genetics class, you learned that height in humans has high heritability, although environmental factors also influence adult height. You correctly explain the meaning of heritability, and your grandfather asks, 'How can height be highly heritable and still be influenced by the environment?' What explanation do you give your grandfather?

1
Explain the concept of heritability: Heritability is a measure of how much of the variation in a trait, such as height, within a population is due to genetic differences among individuals. It is expressed as a proportion, ranging from 0 to 1, where 1 indicates that all variation is genetic and 0 indicates that none is genetic.
Clarify that heritability applies to populations, not individuals: Heritability does not mean that a trait is entirely determined by genetics in every individual. Instead, it reflects the relative contribution of genetic factors to the variation observed in a population under specific environmental conditions.
Discuss the role of environmental factors: Even if a trait like height has high heritability, environmental factors such as nutrition, health during childhood, and access to resources can still influence the expression of the trait. For example, poor nutrition during growth years can limit height potential, even if the genetic predisposition for tall stature exists.
Provide an analogy: Use an analogy to make the concept clearer. For instance, you could say, 'Think of heritability like the blueprint of a house. The blueprint determines the structure, but the final appearance of the house can be influenced by external factors like weather, materials used, and construction quality.'
Conclude with the interaction between genes and environment: Emphasize that traits like height are influenced by both genetic and environmental factors. High heritability means genetics play a significant role in the variation of height within a population, but environmental factors can still modify the outcome for individuals.

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Key Concepts
Here are the essential concepts you must grasp in order to answer the question correctly.
Heritability
Heritability is a statistical measure that estimates the proportion of variation in a trait, such as height, that can be attributed to genetic differences among individuals in a population. A high heritability value indicates that genetics play a significant role in determining that trait, but it does not imply that the trait is solely determined by genes.
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Environmental Influence
Environmental factors encompass a wide range of influences, including nutrition, health, and lifestyle, that can affect an individual's development and traits. Even with high heritability, these factors can modify the expression of genetic potential, meaning that two individuals with similar genetic backgrounds may still exhibit different heights due to their unique environmental experiences.
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Gene-Environment Interaction
Gene-environment interaction refers to the complex interplay between genetic predispositions and environmental conditions. This concept explains that while genetics set a potential range for traits like height, the actual outcome can vary significantly based on environmental factors, illustrating that both genetics and environment are crucial in shaping an individual's characteristics.
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