A pea plant that has the genotype RrGgwwdd is crossed to a plant that has the rrGgWwDd genotype. The R gene controls round versus wrinkled seed, the G gene controls yellow versus green seed, the W gene controls purple versus white flower, and the D gene controls tall versus short plants. Determine the following:
What proportion of the progeny are expected to be round, yellow, purple, and tall?

Cytoplasmic male sterility (CMS) in plants has been exploited to produce hybrid seeds. Specific CMS alleles in the mitochondrial genome can be suppressed by specific dominant alleles in the nuclear genome, called Restorer of fertility alleles, RF. Consider the following cross:

♀CMS 1Rf 1/Rf1 rf2/rf2 × ♂CMS2rf 1/rf1 Rf2/Rf2

What genotypes and phenotypes do you expect in the F₁? If some of the F₁ plants are male fertile, what genotypes and phenotypes do you expect in the F₂?

Three strains of green-seeded lentil plants appear to have the same phenotype. The strains are designated G₁, G₂, and G₃. Each green-seeded strain is crossed to a pure-breeding yellow-seeded strain designated Y. The F₁ of each cross are yellow; however, self-fertilization of F₁ plants produces F₂ with different proportions of yellow- and green-seeded plants as shown below.

Using the allele symbols A and a, B and b, and D and d to represent alleles at segregating genes, give the genotypes of parental and F₁ plants in each cross. 

Draw a pedigree containing two parents and four children. Both of the parents have an AB blood type. The first child is type A, the second child is type AB, and the third child is type B.

The fourth child tests as having blood type O, which is not possible given the parental genotypes. Look at the Figure below and read the description of the molecular process that generates ABO blood group antigens. What other mutation could account for this observation?

Draw a pedigree containing two parents and four children. Both of the parents have AB blood type. The first child is type A, the second child is type AB, and the third child is type B.

Assign the genotypes to these five people.

Go to the OMIM website (http://www.ncbi.nlm.nih.gov/omim) and locate the Search button at the top of the page. Use the search function to look up, one by one, the following three human hereditary diseases that are relatively common in certain populations: 'Tay–Sachs disease' (select OMIM number 272800 from the search results list); 'cystic fibrosis' (select OMIM number 602421 from the search results list); and 'sickle cell anemia' (select OMIM 603903 from the search results list). For each of these diseases, look through the information and provide the following details:

In which population(s) does the disease most commonly occur?

Go to the OMIM website (http://www.ncbi.nlm.nih.gov/omim) and locate the Search button at the top of the page. Use the Search function to look up, one by one, the following three human hereditary diseases that are relatively common in certain populations: 'Tay–Sachs disease' (select OMIM number 272800 from the search results list); 'cystic fibrosis' (select OMIM number 602421 from the search results list); and 'sickle cell anemia' (select OMIM 603903 from the search results list). For each of these diseases, look through the information and provide the following details:

Briefly describe the disease.

Go to the OMIM website (http://www.ncbi.nlm.nih.gov/omim) and locate the Search button at the top of the page. Use the search function to look up, one by one, the following three human hereditary diseases that are relatively common in certain populations: 'Tay–Sachs disease' (select OMIM number 272800 from the search results list); 'cystic fibrosis' (select OMIM number 602421 from the search results list); and 'sickle cell anemia' (select OMIM 603903 from the search results list). For each of these diseases, look through the information and provide the following details:

What gene is mutated in the disease?

Go to the OMIM website (http://www.ncbi.nlm.nih.gov/omim) and locate the Search button at the top of the page. Use the search function to look up, one by one, the following three human hereditary diseases that are relatively common in certain populations: 'Tay–Sachs disease' (select OMIM number 272800 from the search results list); 'cystic fibrosis' (select OMIM number 602421 from the search results list); and 'sickle cell anemia' (select OMIM 603903 from the search results list). For each of these diseases, look through the information and provide the following details:

On which chromosome is the gene for the disease located?