Table of contents

1. Matter and Measurements4h 31m
2. Atoms and the Periodic Table5h 23m
3. Ionic Compounds2h 18m
4. Molecular Compounds2h 18m
5. Classification & Balancing of Chemical Reactions3h 17m
6. Chemical Reactions & Quantities2h 27m
7. Energy, Rate and Equilibrium3h 46m
8. Gases, Liquids and Solids3h 25m
9. Solutions4h 10m
10. Acids and Bases3h 29m
11. Nuclear Chemistry56m
BONUS: Lab Techniques and Procedures1h 38m
BONUS: Mathematical Operations and Functions47m
12. Introduction to Organic Chemistry1h 34m
13. Alkenes, Alkynes, and Aromatic Compounds2h 12m
14. Compounds with Oxygen or Sulfur1h 6m
15. Aldehydes and Ketones1h 1m
16. Carboxylic Acids and Their Derivatives1h 11m
17. Amines39m
18. Amino Acids and Proteins1h 51m
19. Enzymes1h 37m
20. Carbohydrates1h 41m
21. The Generation of Biochemical Energy2h 8m
22. Carbohydrate Metabolism2h 22m
23. Lipids2h 26m
24. Lipid Metabolism1h 45m
25. Protein and Amino Acid Metabolism1h 37m
26. Nucleic Acids and Protein Synthesis2h 54m

26. Nucleic Acids and Protein Synthesis

Steps of DNA Replication

GOB Chemistry

26. Nucleic Acids and Protein Synthesis

Steps of DNA Replication

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Multiple Choice

Below is a close-up of the portion of a DNA replication bubble.

Helicase is shown as a yellow triangle currently moving from left to right. Based on what you know about the creation of new DNA during replication, which is the lagging strand and why?

A is the lagging strand, as DNA is always synthesized in the 5' to 3' manner.

B is the lagging strand, as DNA is always synthesized in the 5' to 3' manner.

A is the lagging strand, as DNA is always synthesized in the 3' to 5' manner.

B is the lagging strand, as DNA is always synthesized in the 3' to 5' manner.

It is impossible to tell, with the information provided.

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Verified step by step guidance

Understand that DNA replication involves the synthesis of new DNA strands complementary to the original template strands.

Recognize that DNA polymerase can only add nucleotides to the 3' end of a growing DNA strand, meaning DNA synthesis occurs in the 5' to 3' direction.

Identify the direction of the helicase movement, which is from left to right in the image, unwinding the DNA double helix.

Determine the orientation of the template strands: Strand A is oriented 5' to 3' from left to right, and Strand B is oriented 3' to 5' from left to right.

Conclude that the lagging strand is synthesized discontinuously in short segments (Okazaki fragments) in the 5' to 3' direction, opposite to the direction of the replication fork movement. Therefore, Strand A is the lagging strand because it is synthesized in the 5' to 3' direction away from the replication fork.