26. Nucleic Acids and Protein Synthesis

Which of the following statements correctly describes the difference between the leading and the lagging strands of DNA during DNA replication?

Below is a close-up of the portion of a DNA replication bubble.

Helicase is shown as a yellow triangle currently moving from left to right. Based on what you know about the creation of new DNA during replication, which is the lagging strand and why?

Suppose that 22% of the nucleotides of a DNA molecule are deoxyadenosine and during replication the relative amounts of available deoxynucleoside triphosphates are 22% dATP, 22% dCTP, 28% dGTP, and 28% dTTP. What deoxynucleoside triphosphate is limiting to the replication? Explain.

What is the function of the enzyme helicase in DNA replication?

What process ensures that the replication of DNA produces identical copies?

How many daughter strands are formed during the replication of DNA?

Copy the following simplified drawing of a DNA replication fork:

a. On the drawing, indicate the direction of synthesis of the new strand labeled A and the location of DNA polymerase on the strand.

What is the difference between DNA polymerase and DNA ligase?

What are Okazaki fragments? What role do they serve in DNA metabolism?