Textbook Question
Give the abbreviation for each of the following coenzymes:
a. reduced form of NAD+
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21. The Generation of Biochemical Energy
Coenzymes in Metabolism
2:10 minutesProblem 49a
Textbook Question
FAD is a coenzyme for dehydrogenation.
a. When a molecule is dehydrogenated, is FAD oxidized or reduced?
Verified step by step guidance1
Understand the concept of dehydrogenation: Dehydrogenation is a chemical reaction in which hydrogen atoms are removed from a molecule. This process typically involves the transfer of electrons and protons.
Recall the role of FAD (Flavin Adenine Dinucleotide): FAD is a coenzyme that participates in redox reactions, meaning it can either accept or donate electrons during these reactions.
Determine what happens to FAD during dehydrogenation: When a molecule is dehydrogenated, it loses hydrogen atoms (which include electrons). These electrons are transferred to FAD, meaning FAD gains electrons.
Apply the definition of reduction: Reduction is the gain of electrons. Since FAD gains electrons during dehydrogenation, it is reduced in the process.
Conclude the answer: FAD is reduced when a molecule is dehydrogenated because it accepts electrons from the molecule undergoing the reaction.
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Key Concepts
Here are the essential concepts you must grasp in order to answer the question correctly.
Dehydrogenation
Dehydrogenation is a chemical reaction that involves the removal of hydrogen atoms from a molecule. This process typically results in the oxidation of the substrate, as it loses electrons along with the hydrogen. Dehydrogenation is crucial in metabolic pathways, particularly in cellular respiration, where it helps convert substrates into energy-rich molecules.
FAD as a Coenzyme
FAD (flavin adenine dinucleotide) is a coenzyme that plays a vital role in various biological oxidation-reduction reactions. It acts as an electron carrier, accepting electrons during the dehydrogenation process. When FAD accepts electrons, it is reduced to FADH2, which can later donate these electrons in the electron transport chain to produce ATP.
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Oxidation and Reduction
Oxidation and reduction are complementary chemical processes that involve the transfer of electrons between substances. Oxidation refers to the loss of electrons (or hydrogen), while reduction refers to the gain of electrons (or hydrogen). In the context of dehydrogenation, the substrate is oxidized, and FAD is reduced, highlighting the interconnected nature of these reactions in metabolic pathways.
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