BackIntroduction to Medical Terminology: Components, Word Roots, Prefixes, Suffixes, and Plural Endings
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Ch. 1 Introduction to Medical Terminology
Medical Term Components
Medical terms are constructed from specific word parts, each contributing to the overall meaning of the term. Understanding these components is essential for interpreting and forming medical vocabulary.
Constructed Terms: Built from word parts (roots, prefixes, suffixes, combining vowels).
Eponyms: Terms derived from people's names (e.g., Lou Gehrig’s disease).
Component | Definition | Example |
|---|---|---|
Word Root | Core meaning, usually a body system or structure | cardi (heart) |
Combining Vowel | Links word parts, often 'o' | cardi/o |
Prefix | Added to the beginning, modifies meaning (direction, quantity, etc.) | hypo- (below) |
Suffix | Added to the end, modifies meaning (condition, procedure, etc.) | -itis (inflammation) |
Example: Electrocardiogram = electricity (electro-) + heart (cardi/o) + record/image (-gram)

Defining Medical Terms:
First, define the suffix (condition/procedure).
Then, the prefix (direction, quantity, etc.).
Finally, the word root (core meaning).
Example: Hypoglycemia = hypo- (below) + glyc (sugar) + -emia (blood condition) → Low blood sugar condition.
Forming Terms from Word Parts
Medical terms are formed by combining the components in a specific order:
Determine if a combining vowel is needed (use if suffix starts with a consonant or when joining two roots).
Add the suffix to the end of the word root.
Add the prefix to the beginning of the word root.
Interpret the meaning from the components.
Example: anti- (against) + path/o (disease) + -genic (producing) = Antipathogenic (producing against disease).
Word Roots and Combining Forms
Common Word Roots
Word roots provide the core meaning of medical terms, often indicating a body part or system.
Combining Form | Definition |
|---|---|
append/o | appendix |
carcin/o | cancerous |
cis/o | to cut |
dermat/o | skin |
encephal/o | brain |
enter/o | small intestine |
eti/o | cause (of disease) |
gastr/o | stomach |
gynec/o | woman, female |
hemat/o | blood |
laryng/o | larynx (voice box) |
macr/o | large |
mamm/o | breast |
nephr/o | kidney |
ophthalm/o | eye |
ot/o | ear |
path/o | disease |
pulm/o | lung |
rhin/o | nose |

Prefixes
Prefixes Indicating Numbers and Amounts
Prefixes can indicate the number, size, or amount related to the root word.
Prefix | Definition | Example/Memory Tool |
|---|---|---|
ambi- | both | ambidextrous |
centi- | hundred | centimeter |
di- | two | dilemma |
milli- | thousand | millimeter |
mono-, uni- | one | unicycle |
multi-, poly- | many, much | multicultural |
nulli- | none | null and void |
semi-, hemi- | half | semicircle |

Prefixes Indicating Qualities
These prefixes describe attributes or characteristics of a condition.
Prefix | Definition | Example/Memory Tool |
|---|---|---|
brady- | slow | Brady the turtle |
dys- | difficult, bad, painful | dyslexia |
eu- | good | euphoria |
heter- | different | heterogeneous |
mal- | bad | malfunction |
mega-, megal- | very large | megaphone |
neo- | new | neonate |
tachy- | fast | tachometer |
ultra- | beyond normal | ultra-fast |

Prefixes Indicating Position and Placement
These prefixes specify location, direction, or spatial relationships.
Prefix | Definition |
|---|---|
ante-, pre- | in front of |
dorsi-, dorso- | behind |
infer-, infra-, hypo- | below |
circum- | around |
peri- | surrounding |
ep-, epi- | over, above, on top of |
ab- | away from |
ad- | toward |
ec- | outside, out |
intra- | within |
inter- | between |
para- | beside, near |
dia- | through |
Suffixes
General Use Suffixes
Suffixes are added to the end of word roots to modify their meaning, often indicating a condition, procedure, or specialty.
Suffix | Definition | Example |
|---|---|---|
-algia | pain | gastralgia (stomach pain) |
-drome | symptoms occurring together | syndrome |
-cide | to kill | bactericide |
-gen, -genic, -genesis | to form or produce | embryogenesis |
-stasis | control/stop | hemostasis |
-blast | immature cell | hepatoblast |
-cyte | cell | erythrocyte |
-logy | study of | hepatology |
-therapy | treatment | psychotherapy |
-thermy | heat | endothermy |
Grammatical Suffixes
These suffixes convert word roots into nouns, adjectives, or diminutives.
Suffix | Type | Example |
|---|---|---|
-ia, -osis, -ism | Noun | hyperhidrosis, embolism |
-iatry, -ician, -ist | Specialist | psychiatry, pediatrician, cardiologist |
-ac, -al, -ar, -ary, -ic, -ile | Adjective | cardiac, congenital, muscular, urinary, cephalic, infantile |
-icle, -ole, -ula, -ule | Diminutive | ventricle, arteriole, macula, pustule |
Suffixes for Pathological Conditions
These suffixes describe diseases, conditions, or symptoms.
Suffix | Definition | Example |
|---|---|---|
-mania | obsession | pyromania |
-phobia | fear | pyrophobia |
-edema | swelling | lymphedema |
-emesis | vomiting | hyperemesis |
-asthenia | weakness | myasthenia |
-itis | inflammation | arthritis |
-malacia | softening | osteomalacia |
-megaly | enlargement | hepatomegaly |
-oma | tumor | carcinoma |
-pathy | disease | nephropathy |
-penia | deficiency | osteopenia |
-phasia | to speak | aphasia |
-plegia | paralysis | hemiplegia |
-rrhage | bursting forth | hemorrhage |
-rrhea | flow, discharge | diarrhea |
-rrhexis | rupture | hysterorrhexis |
Suffixes for Diagnostic and Surgical Procedures
Suffix | Definition | Example |
|---|---|---|
-tomy | incision | gastrotomy |
-ectomy | surgical removal | gastrectomy |
-stomy | new opening | colostomy |
-centesis | surgical puncture to remove fluid | amniocentesis |
-desis | binding | arthrodesis |
-rrhaphy | suture | herniorrhaphy |
-graph | recording instrument | polygraph |
-graphy | recording technique | angiography |
-meter | measuring instrument | thermometer |
-metry | measuring technique | spirometry |
-scope | examination instrument | microscope |
-scopy | examination technique | colonoscopy |
Plural Endings
Rules for Forming Plurals in Medical Terms
Many medical terms have Latin or Greek origins, and their plural forms follow specific rules:
Singular Ending | Plural Ending | Example |
|---|---|---|
-y | -ies | artery → arteries |
-is | -es | diagnosis → diagnoses |
-us | -i | nucleus → nuclei |
-a | -ae | vertebra → vertebrae |
-um, -on | -a | ovum → ova, ganglion → ganglia |
-en | -ina | foramen → foramina |
-nx | -nges | phalanx → phalanges |
-ax, -ex, -ix | -ces | thorax → thoraces, appendix → appendices |
Example: The plural of metastasis is metastases.
Additional info: These rules are essential for accurate communication in medical documentation and reporting.