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Medical Terminology and Anatomy of the Gastrointestinal System

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Gastroenterology: Medical Terminology

Word Roots and Structure

Medical terminology often uses word roots, prefixes, and suffixes to describe anatomical structures and diseases. Understanding these components is essential for proficiency in medical language.

  • gastr/o-: means stomach

  • enter/o-: means intestine

  • -logy: means study of

Medical terminology breakdown: gastr/o-, enter/o-, -logy

Example: Gastroenterology is the study of the stomach and intestines.

Anatomy of the Gastrointestinal (GI) System

Overview of GI System

The gastrointestinal system consists of organs and glands connected in a pathway. Food enters the body, is digested, nutrients are absorbed into the blood, and undigested waste is eliminated.

Human body showing GI organs

Oral Cavity and Pharynx

The oral cavity contains the teeth, gums, tongue, and the hard and soft palates. Food passes from the oral cavity into the pharynx (throat) and then the esophagus.

  • Teeth: Responsible for mastication (chewing).

  • Gums: Support the teeth.

  • Tongue: Perceives taste and aids in swallowing.

  • Hard and Soft Palate: Form the roof of the mouth.

Anatomy of oral cavity and pharynx

Salivary Glands

Salivary glands produce saliva, which begins the process of digestion and lubricates food for swallowing. The major salivary glands are:

  • Parotid glands: Located anterior to the ear.

  • Sublingual glands: Located under the tongue.

  • Submandibular glands: Located inferior to the mandible.

Salivary glands in the face

Pharynx and Larynx

The pharynx is a common passageway for air and food, divided into three parts: nasopharynx, oropharynx, and laryngopharynx. The larynx is just inferior to the pharynx and remains open during breathing and speaking, but closes during swallowing to prevent food from entering the trachea.

  • Epiglottis: Seals the opening to the larynx during swallowing.

Anatomy of pharynx and larynx

Esophagus

The esophagus is a muscular tube connecting the pharynx to the stomach. Peristalsis moves food through the esophagus.

  • Upper esophagus: Located in the neck.

  • Lower esophagus: Located in the thoracic cavity.

Esophagus and stomach anatomy

Stomach Anatomy

The stomach is divided into four parts: cardia, fundus, body, and pylorus. The omentum is a fatty membrane protecting abdominal organs. The stomach's mucosa forms rugae, which expand to accommodate food.

  • Cardia: Where the stomach joins the esophagus.

  • Fundus: Rounded upper portion.

  • Body: Large curved region.

  • Pylorus: Narrow last part joining the duodenum.

  • Rugae: Folds in the gastric mucosa.

  • Sphincters: Lower esophageal and pyloric sphincters regulate passage of food.

Stomach anatomy and omentum

Diseases of the GI System

Oral Cavity and Salivary Gland Diseases

  • Glossitis: Infection or inflammation of the tongue.

  • Sialolithiasis: Presence of a stone in a salivary gland causing swelling.

Esophagus and Stomach Diseases

  • Dyspepsia: Temporary epigastric pain; indigestion.

  • Esophageal varix: Swollen, protruding vein in the esophageal mucosa.

  • Gastritis: Acute or chronic inflammation of the stomach.

  • Gastroenteritis: Acute infection or inflammation of the stomach and intestines.

  • Gastroesophageal reflux disease (GERD): Chronic irritation due to reflux of stomach acid into the esophagus.

  • Peptic ulcer disease (PUD): Chronic irritation and erosion of the mucosa due to an ulcer.

  • Stomach cancer: Cancerous tumor of the stomach, often caused by H. pylori.

Esophageal varices Gastric ulcer with bleeding

Diagnostic and Surgical Procedures

Endoscopy and Related Procedures

Endoscopy uses a flexible, fiberoptic scope to examine the GI system internally. Endoscopic retrograde cholangiopancreatography (ERCP) visualizes the bile and pancreatic ducts using contrast dye.

Endoscopic retrograde cholangiopancreatography (ERCP)

Nasogastric and PEG Tubes

Nasogastric (NG) tubes are inserted through the nose into the stomach for feeding or drainage. Percutaneous endoscopic gastrostomy (PEG) tubes are inserted through the abdominal wall for permanent feeding access.

Nasogastric tube insertion PEG tube insertion

Radiologic Procedures

Upper gastrointestinal series (UGI) uses barium contrast to outline the esophagus, stomach, and duodenum. Oral cholecystography (OCG) uses iodinated contrast dye to visualize the gallbladder.

Upper gastrointestinal series with barium

Anatomy: Small and Large Intestines

Small Intestine

The small intestine consists of the duodenum, jejunum, and ileum. It contains thousands of villi to maximize absorption of nutrients and water.

  • Duodenum: First segment, C-shaped, ~10 inches long.

  • Jejunum: Middle segment, ~8 feet long.

  • Ileum: Third segment, ~12 feet long.

Small and large intestine anatomy Villi in the small intestine

Diseases of the Small Intestine

  • Ileus: Absence of normal peristalsis.

  • Intussusception: Telescoping of one intestinal segment inside another.

  • Volvulus: Twisting or rotating of the intestine.

Intussusception of the intestine Volvulus of the intestine

Large Intestine

The large intestine runs from the small intestine to the outside surface of the body. It consists of the cecum, colon, and rectum. The colon is divided into ascending, transverse, descending, and sigmoid parts.

Large intestine anatomy

Diseases of the Cecum and Colon

  • Appendicitis: Inflammation and infection of the appendix.

  • Colon cancer: Cancerous tumor of the colon.

  • Diverticulum/Diverticulitis: Pouches in the colon wall that can become infected.

  • Gluten sensitivity enteropathy: Autoimmune reaction to gluten.

  • Inflammatory bowel disease (IBD): Chronic inflammation (Crohn disease, ulcerative colitis).

  • Irritable bowel syndrome (IBS): Functional disorder of the colon.

  • Polyposis: Numerous polyps in the colon.

Rectum and Anus

Anatomy and Diseases

  • Hemorrhoids: Swollen veins in the rectum.

  • Proctitis: Inflammation of the rectum and anus.

  • Rectocele: Hernia in the wall of the rectum.

Defecation and Feces

  • Constipation: Failure to have regular, soft bowel movements.

  • Diarrhea: Frequent, loose, watery feces.

  • Flatulence: Excessive gas in the stomach or intestines.

  • Hematochezia: Blood in the feces.

  • Steatorrhea: Feces containing undigested fats.

Abdominopelvic Cavity and Accessory Organs

Liver

The liver is the largest solid organ, producing bile and processing nutrients. Diseases include cirrhosis, hepatomegaly, hepatitis, jaundice, and liver cancer.

Normal and diseased liver Jaundice in the eye (scleral icterus) CT scan showing liver cancer Ascites due to liver disease

Gallbladder and Bile Ducts

The gallbladder stores and concentrates bile. Diseases include cholangitis, cholecystitis, cholelithiasis, and gallbladder cancer.

Gallstones in biliary and pancreatic ducts Gallbladder with gallstones Laparoscopic cholecystectomy

Pancreas

The pancreas secretes digestive enzymes into the duodenum. Diseases include pancreatic cancer and pancreatitis.

Pancreas anatomy

Physiology of Digestion

Mechanical Digestion

  • Mastication: Chewing by the teeth.

  • Deglutition: Swallowing food.

  • Peristalsis: Muscular contractions moving food.

Chemical Digestion

  • Amylase: Breaks down carbohydrates.

  • Pepsin: Breaks down proteins.

  • Gastrin: Stimulates release of hydrochloric acid and pepsinogen.

  • Hydrochloric acid: Breaks down food fibers.

  • Cholecystokinin: Stimulates gallbladder to release bile.

  • Bile: Breaks down fats.

  • Lactase: Breaks down milk sugars.

Absorption and Elimination

  • Absorption: Nutrients and water absorbed mainly in the small intestine.

  • Elimination: Removal of undigested waste as feces.

Laboratory Tests and Diagnostic Procedures

  • Albumin: Major protein in blood, produced by the liver.

  • Cologuard®: DNA screening test for cancer in stool.

  • Culture and sensitivity (C & S): Stool test for bacteria.

  • Fecal occult blood test: Detects hidden blood in feces.

  • Ova and parasites (O & P): Stool test for parasites.

  • Helicobacter pylori tests: Detects H. pylori infection.

  • Liver function tests (LFTs): Panel of blood tests for liver function.

Common Drugs for GI Diseases

  • Antacid drugs: Neutralize stomach acid.

  • Antibiotic drugs: Treat bacterial infections.

  • Antidiarrheal drugs: Slow peristalsis and increase water absorption.

  • Antiemetic drugs: Treat nausea and vomiting.

  • Antispasmodic drugs: Decrease peristalsis and spasms.

  • Bile acid drugs: Decrease cholesterol production for gallstones.

  • H2 blocker drugs: Block histamine receptors to reduce acid.

  • Laxative drugs: Treat constipation.

  • Proton pump inhibitor drugs: Block production of hydrochloric acid.

Abbreviation Summary

Abbreviation

Definition

ABD

abdomen

ALP

alkaline phosphatase

ALT

alanine aminotransferase

AST

aspartate aminotransferase

BE

barium enema

BM

bowel movement

C&S

culture and sensitivity

CAT, CT

computerized axial tomography

CBD

common bile duct

EGD

esophagogastroduodenoscopy

ERCP

endoscopic retrograde cholangiopancreatography

GERD

gastroesophageal reflux disease

IBD

inflammatory bowel disease

IBS

irritable bowel syndrome

LFTs

liver function tests

MRI

magnetic resonance imaging

N&V

nausea and vomiting

NG

nasogastric

OCG

oral cholecystogram

PUD

peptic ulcer disease

RLQ

right lower quadrant

RUQ

right upper quadrant

UGI

upper gastrointestinal (series)

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