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Medical Terminology: Common Prefixes and Their Meanings

Study Guide - Smart Notes

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Medical Terminology Prefixes

Introduction

Prefixes are essential components of medical terminology. They are added to the beginning of root words to modify their meaning, often indicating location, time, number, or status. Understanding common prefixes helps in deciphering complex medical terms and enhances communication in healthcare settings.

Common Medical Prefixes and Their Definitions

The following table summarizes frequently used medical prefixes, their definitions, and examples of their application in medical terms.

Prefix

Definition

Example

supra-

above; over; beyond

suprarenal (above the kidney)

trans-

across; through

transdermal (through the skin)

post-

after; behind

postoperative (after surgery)

anti-

against

antibiotic (against life, i.e., bacteria)

contra-

against

contraceptive (against conception)

pan-

all

pancytopenia (deficiency of all blood cells)

par-

apart from

paracrine (signaling apart from the cell)

circum-

around

circumoral (around the mouth)

peri-

around; about

pericardium (around the heart)

ex-

away from; outside

exhale (to breathe out)

retro-

backward; behind

retroperitoneal (behind the peritoneum)

dys-

bad; difficult; painful; disordered

dysfunction (abnormal function)

mal-

bad; poor

malnutrition (poor nutrition)

ante-

before; in front

antepartum (before birth)

pre-

before; in front

prenatal (before birth)

infra-

beneath; below; under

infrascapular (below the scapula)

sub-

beneath; under

subcutaneous (under the skin)

inter-

between

intercostal (between the ribs)

meta-

beyond; after; change

metastasis (change of place, spread of disease)

ultra-

beyond; excess

ultrasound (beyond sound, high-frequency sound waves)

ambi-

both; both sides

ambidextrous (able to use both hands)

de-

down; from

dehydrate (remove water)

cata-

down; under; against; lower

catabolism (breakdown of substances)

hyper-

excessive; above

hypertension (high blood pressure)

pseudo-

false

pseudocyst (false cyst)

primi-

first

primigravida (first pregnancy)

quadri-

four

quadriplegia (paralysis of four limbs)

dis-

free of; to undo; double; negative

disinfect (to free from infection)

ab-

from; away from; absent

abduction (movement away from midline)

hemi-

half

hemiplegia (paralysis of one side)

semi-

half

semilunar (half-moon shaped)

in-

in; inside; within; not

inhalation (breathing in), inactive (not active)

idio-

individual

idiopathic (of unknown individual cause)

sym-

joined; together

symbiosis (living together)

syn-

joined; together

syndrome (group of symptoms occurring together)

mega-

large

megacolon (abnormally large colon)

bio-

life

biology (study of life)

homeo-

likeness; same

homeostasis (state of sameness)

multi-

many

multicellular (many cells)

poly-

many; much

polyuria (excessive urination)

meso-

middle

mesoderm (middle layer of embryo)

cine-

movement

cinematography (recording movement)

juxta-

near; beside

juxtaglomerular (near the glomerulus)

para-

near; beside; beyond; two like parts

parathyroid (beside the thyroid)

nulli-

none

nullipara (woman who has never given birth)

im-

not

immobile (not movable)

non-

not

noninvasive (not entering the body)

ana-

not; without; against

anaphylaxis (against protection)

uni-

one

unilateral (one side)

mono-

one; single

monocyte (single cell)

milli-

one-thousandth

milligram (one-thousandth of a gram)

ecto-

outside

ectoderm (outer layer of embryo)

extra-

outside; beyond

extracellular (outside the cell)

exo-

outward

exocrine (secreting outward)

tachy-

rapid

tachycardia (rapid heart rate)

oxy-

rapid; sharp

oxytocin (quick birth)

rube-

red

rubella (disease causing red rash)

homo-

same

homogeneous (of the same kind)

auto-

self

autoimmune (immune response against self)

hypno-

sleep; hypnosis

hypnotic (inducing sleep)

brady-

slow

bradycardia (slow heart rate)

echo-

sound

echocardiogram (ultrasound of the heart)

pachy-

thick

pachyderma (thick skin)

tri-

three

tricuspid (three cusps)

dia-

through; between

dialysis (separation through a membrane)

per-

through; intense

percutaneous (through the skin)

con-

together; with

congenital (born with)

ad-

toward; increase

adduction (movement toward midline)

bi-

two; double

bicuspid (two cusps)

hypo-

under; below; beneath; less than normal

hypoglycemia (low blood sugar)

aniso-

unequal

anisocytosis (unequal cell size)

epi-

upon; over; after

epidermis (upon the skin)

hydro-

water

hydrocephalus (water in the brain)

eu-

well; easily; good; normal

eupnea (normal breathing)

alb-

white

albino (person with white skin and hair)

intra-

within

intravenous (within a vein)

endo-

within; inner

endoscope (instrument to view inside)

an-

without; not

anemia (without enough red blood cells)

a-

without; not; away from

apnea (without breathing)

Key Points for Studying Medical Prefixes

  • Prefixes are attached to the beginning of root words to alter their meaning.

  • They often indicate location, number, time, status, or quality.

  • Some prefixes have similar meanings (e.g., sub- and infra- both mean "below"), so context is important.

  • Combining prefixes with roots and suffixes forms complex medical terms (e.g., hypoglycemia = hypo- (low) + glyc (sugar) + -emia (blood condition)).

Examples and Applications

  • Hypertension: hyper- (excessive) + tension (pressure) = high blood pressure.

  • Subcutaneous: sub- (under) + cutaneous (skin) = under the skin.

  • Bradycardia: brady- (slow) + cardia (heart) = slow heart rate.

Additional info:

  • Some prefixes can have more than one meaning depending on the context (e.g., in- can mean "in" or "not").

  • Learning prefixes, roots, and suffixes systematically helps in understanding unfamiliar medical terms.

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