Multiple Choice
Type III hypersensitivity is caused by the immune system’s reaction to immune complexes. Immune complexes are made of aggregates of which of the following?
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27. Immunological Disorders
Type III Hypersensitivities
Multiple Choice
Which of the following statements about immune complexes is false regarding hypersensitivity reactions?
A
Small immune complexes that evade phagocytosis are more problematic than large immune complexes.
B
Immune complexes are often removed from the body by phagocytosis.
C
Immune complexes directly damage tissues & cells by releasing hydrolytic enzymes.
D
Immune complexes are an aggregate of antibodies bound to antigens.
Verified step by step guidance1
Step 1: Understand what immune complexes are. Immune complexes are aggregates formed when antibodies bind to antigens. This is a fundamental concept in immunology and hypersensitivity reactions.
Step 2: Recognize the role of immune complexes in hypersensitivity. In type III hypersensitivity reactions, immune complexes can deposit in tissues and trigger inflammation.
Step 3: Analyze the fate of immune complexes. Large immune complexes are usually cleared efficiently by phagocytosis, while small immune complexes can evade clearance and cause more problems by depositing in tissues.
Step 4: Evaluate the mechanism of tissue damage. Immune complexes themselves do not directly release hydrolytic enzymes; instead, they activate complement and recruit inflammatory cells, which then release enzymes causing tissue damage.
Step 5: Identify the false statement by comparing the options to the known mechanisms. The false statement is the one claiming that immune complexes directly damage tissues by releasing hydrolytic enzymes, as this is actually the role of recruited inflammatory cells, not the immune complexes themselves.
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