Multiple Choice
T-dependent antigens can stimulate B cells to become activated but require _________ assistance.
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20. Adaptive Immunity
T Dependent & T Independent Antigens
Multiple Choice
Which of the following is a step required for activation of a B cell by a T-dependent antigen?
A
The antigen is presented on MHC class I proteins of the T cell.
B
The antigen binds to the BCR of a naive B cell.
C
The antigen is presented on MHC class II proteins of the B cell.
D
TH cell recognizes the antigen as a pathogen and triggers apoptosis in the B cell.
E
TH cell recognizes the antigen as a pathogen and activates the B cell causing the B cell to secrete antibodies.
F
B, C, & E.
G
A, B & E.
Verified step by step guidance1
Understand the role of B cells and T cells in the immune response. B cells are responsible for producing antibodies, while T cells help activate B cells and other immune cells.
Recognize that T-dependent antigens require the help of T helper (TH) cells for B cell activation. This involves a series of interactions between the B cell and the TH cell.
Identify that the antigen must first bind to the B cell receptor (BCR) on a naive B cell. This is the initial step in the activation process.
Understand that the antigen is then processed and presented on MHC class II proteins of the B cell. This presentation is crucial for the interaction with the TH cell.
Recognize that the TH cell must recognize the antigen-MHC class II complex on the B cell. This recognition leads to the activation of the B cell, allowing it to proliferate and differentiate into plasma cells that secrete antibodies.
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