Multiple Choice
Which of the following is a step required for activation of a B cell by a T-dependent antigen?
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20. Adaptive Immunity
T Dependent & T Independent Antigens
Multiple Choice
T-independent antigens:
A
Interact with MHC I molecules.
B
Require the involvement of T cells.
C
Include pathogen associated polysaccharides.
D
Are usually pathogen associated nucleic acids.
Verified step by step guidance1
Understand the concept of T-independent antigens: These are antigens that can trigger an immune response without the direct involvement of T-helper cells.
Recognize that T-independent antigens typically include polysaccharides found on the surface of pathogens, such as bacteria. These polysaccharides can directly activate B cells.
Differentiate between T-independent and T-dependent antigens: T-dependent antigens require the help of T cells to activate B cells, whereas T-independent antigens do not.
Note that T-independent antigens do not interact with MHC I molecules, as MHC I is involved in presenting antigens to cytotoxic T cells, not in the activation of B cells.
Understand that T-independent antigens are not usually associated with nucleic acids, as nucleic acids typically require processing and presentation by MHC molecules, which involves T cells.
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