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Multiple Choice
Which of the following is a mechanism by which neutrophils destroy microbial invaders?
A
Presentation of antigens to T cells
B
Secretion of interferons
C
Phagocytosis followed by production of reactive oxygen species
D
Antibody production
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Verified step by step guidance
1
Understand the role of neutrophils in the immune system: Neutrophils are a type of white blood cell primarily involved in the innate immune response, acting as first responders to microbial invasion.
Recall the main mechanisms neutrophils use to destroy microbes: Neutrophils engulf pathogens through a process called phagocytosis, where the microbe is internalized into a vesicle called a phagosome.
Recognize what happens after phagocytosis: The phagosome fuses with lysosomes to form a phagolysosome, where reactive oxygen species (ROS) and enzymes are produced to kill and digest the engulfed microbes.
Differentiate neutrophil functions from other immune cells: For example, antigen presentation to T cells is mainly performed by dendritic cells and macrophages, interferon secretion is typical of virus-infected cells and some immune cells, and antibody production is a function of B cells.
Conclude that the mechanism by which neutrophils destroy microbial invaders is phagocytosis followed by the production of reactive oxygen species, which effectively kills the pathogens inside the neutrophil.