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Multiple Choice
Which type of hypersensitivity involves the production of naturally forming, M class antibodies that trigger immune reactions to foreign cells?
A
Type I only.
B
Type II only.
C
Types I & II.
D
Type III only.
E
Type I & III only.
F
Type II & III only.
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Verified step by step guidance
1
Step 1: Understand the classification of hypersensitivity reactions. There are four main types: Type I (immediate), Type II (antibody-mediated), Type III (immune complex-mediated), and Type IV (cell-mediated).
Step 2: Identify the role of M class antibodies (IgM). IgM antibodies are naturally occurring and are often involved in early immune responses, particularly in recognizing foreign cells such as blood group antigens.
Step 3: Recall that Type II hypersensitivity involves IgG or IgM antibodies binding to antigens on the surface of cells, leading to cell destruction or dysfunction. This is typical in reactions against foreign cells.
Step 4: Recognize that Type I hypersensitivity involves IgE antibodies and allergic reactions, while Type III involves immune complexes formed by IgG or IgM but not specifically targeting foreign cells directly.
Step 5: Conclude that the hypersensitivity type involving naturally forming IgM antibodies reacting to foreign cells corresponds to Type II hypersensitivity.