Multiple Choice
The redundancy of the genetic code is a consequence of ______.
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15. Central Dogma & Gene Regulation
Genetic Code
Multiple Choice
Which of the following sequences of nucleotides are possible in the template strand of DNA that would code for the polypeptide sequence Phe–Leu–Ile–Val?
A
5′–TTG–CTA–CAG–TAG–3′.
B
5′–AUG–CTG–CAG–TAT–3′.
C
3′–AAA–AAT–ATA–ACA–5′.
D
3′–AAA–GAA–TAA–CAA–5′.
Verified step by step guidance1
Understand that the problem is asking for the DNA template strand that codes for a specific polypeptide sequence: Phe–Leu–Ile–Val.
Recall that the DNA template strand is complementary to the mRNA strand, which is read in the 5' to 3' direction during translation.
Use the genetic code chart to find the mRNA codons for the amino acids: Phe (UUU or UUC), Leu (UUA, UUG, CUU, CUC, CUA, CUG), Ile (AUU, AUC, AUA), and Val (GUU, GUC, GUA, GUG).
Determine the complementary DNA template strand for the mRNA codons. For example, if the mRNA codon for Phe is UUU, the DNA template strand would be AAA.
Check the given options to see which sequence matches the complementary DNA template strand for the mRNA codons that code for Phe–Leu–Ile–Val. The correct sequence is 3′–AAA–GAA–TAA–CAA–5′.
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