Which statement best distinguishes selective toxicity from host toxicity in antimicrobial therapy?

Selective toxicity occurs when drugs affect both microbes and host equally, and host toxicity only refers to allergic reactions mediated by the immune system.

Selective toxicity is only measured in vitro and has no clinical relevance; host toxicity is the only factor clinicians consider when prescribing antimicrobials.

Selective toxicity refers to damaging microbial targets while sparing host cells, whereas host toxicity refers to adverse effects that harm the patient’s organs or tissues.

Selective toxicity is the same as nephrotoxicity specifically, whereas host toxicity refers exclusively to liver damage caused by antimicrobials.