Question 1

Which of the following statements best describes a chiral molecule?

Accepted Answer

A molecule that is not superposable on its mirror image.

Question 2

Which of the following is true about enantiomers?

Accepted Answer

They are stereoisomers that are nonsuperposable mirror images.

Question 3

A carbon atom bonded to four different groups is called:

Accepted Answer

A stereocenter.

Question 4

Which of the following molecules is chiral?

Accepted Answer

2-butanol ($$CH_3CH(OH)CH_2CH_3)$$

Question 5

Which statement about diastereomers is correct?

Accepted Answer

Diastereomers are stereoisomers that are not mirror images.

Question 6

Which of the following pairs are enantiomers?

Accepted Answer

Two molecules of 2-butanol with opposite configurations at the chiral center

Question 7

What is the minimum requirement for a molecule to be chiral?

Accepted Answer

It must lack a center of symmetry and have at least one stereocenter.

Question 8

Which of the following best describes a stereoisomer?

Accepted Answer

Compounds with the same molecular formula and connectivity but different spatial arrangement of atoms.

Question 9

Which of the following is NOT a property of enantiomers?

Accepted Answer

They are superposable on each other.

Question 10

Consider the molecule 1,4-dimethylcyclohexane. Which statement is true?

Accepted Answer

cis- and trans-1,4-dimethylcyclohexane are diastereomers.

Question 11

Which of the following molecules can exist as configuration isomers?

Accepted Answer

2-butene ($$CH_3CH=$$CHCH_3$$)

Question 12

A molecule with two stereocenters can have how many possible stereoisomers?

Accepted Answer

$$4$$

Question 13

Which of the following is a correct statement about cis-trans isomerism?

Accepted Answer

It is a type of configuration isomerism.

Question 14

Which of the following molecules has a plane of symmetry?

Accepted Answer

trans-2-butene

Question 15

Which of the following statements about configuration isomers is FALSE?

Accepted Answer

They are always mirror images of each other.

Question 16

Which of the following is a real-world example of chirality affecting biological activity?

Accepted Answer

The two enantiomers of thalidomide, where one is therapeutic and the other is teratogenic.

Question 17

Which of the following is true about a molecule with a center of symmetry?

Accepted Answer

It cannot be chiral.

Question 18

How can you experimentally distinguish between two enantiomers?

Accepted Answer

By measuring their optical rotation with plane-polarized light.

Question 19

Which of the following statements about stereoisomers is correct?

Accepted Answer

Stereoisomers have the same molecular formula and connectivity but differ in spatial arrangement.

Question 20

Which of the following molecules is achiral?

Accepted Answer

trans-2-butene

Chirality and Stereoisomerism in Organic Molecules (Chapter 3)

Study Guide - Practice Questions