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Substitution and Elimination Reactions of Alkyl Halides: Mechanisms, Selectivity, and Synthetic Applications

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Nucleophilic Substitution

Good Leaving Groups

SN2 Reaction

SN1 Reaction

Substitution Comparison

E2 Mechanism

E1 Reaction

Leaving Groups

Nucleophiles and Basicity

SN1 SN2 E1 E2 Chart (Big Daddy Flowchart)

Cumulative Substitution/Elimination

Williamson Ether Synthesis