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Social Determinants of Health: Mechanisms, Pathways, and Inequalities

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Social Determinants of Health

Defining Social Determinants of Health

The social determinants of health (SDOH) are the conditions in which people are born, grow, live, work, and age. These determinants are shaped by the distribution of money, power, and resources at global, national, and local levels. SDOH are primary predictors of health outcomes, often exerting stronger effects than individual behaviors such as smoking, diet, or exercise.

  • Key determinants: early life, education, employment and working conditions, food security, geography, health care services, housing, income and its distribution, social exclusion, social safety net, unemployment and employment security.

  • Social locations: disability, gender, immigrant status, Indigenous ancestry, race.

Box 1.2: The Social Determinants of Health Framework

Upstream vs Downstream Interventions

Addressing health requires moving beyond treating symptoms to tackling root causes. Upstream interventions focus on changing social and structural factors that lead to poor health, while downstream interventions address immediate health needs.

  • Upstream: Policy, education, social supports.

  • Downstream: Therapy, medical treatment.

Upstream and downstream health interventions cartoon

Equality, Equity, and Reality in Health

Conceptualizing Fairness

Health outcomes are influenced by how resources and opportunities are distributed. Equality means everyone gets the same resources, equity means resources are distributed based on need, and reality reflects actual disparities.

  • Equality: Uniform distribution, may not address needs.

  • Equity: Adjusted distribution, aims to level the playing field.

  • Reality: Shows persistent gaps and structural barriers.

Equality vs Equity vs Reality cartoon

Health Gradients and Social Factors

The Health Gradient

The health gradient describes stepwise differences in health outcomes across socioeconomic groups. Individuals face increasing health hazards as they move down the gradient, with poverty, poor housing, and environmental risks compounding disadvantage.

  • Health hazards: Poverty, inadequate food/nutrition, lack of education, unemployment, poor housing, environmental health hazards.

  • Preventive action: Often limited by structural barriers.

The Health Gradient diagram

Premature Years of Life Lost and Income-Related Causes

Premature Mortality in Canada

Premature years of life lost (YLL) are disproportionately caused by income-related factors. Data from urban Canada (1996) show neoplasms, income-related causes, and circulatory diseases as leading contributors.

  • Neoplasms: 30.9%

  • Income-related: 23.1%

  • Circulatory: 17.6%

Percentage of premature years of life lost to Canadians in urban Canada due to various causes, 1996

Income-Related Disease Burden

Specific diseases contribute to income-related premature YLL, with circulatory diseases and injuries being most prominent.

  • Circulatory: 21.8%

  • Injuries: 16.9%

  • Neoplasms: 14%

Percentage of income-related premature years of life lost caused by specific diseases in urban Canada, 1996

Income Inequality and Excess Deaths

Risk Ratios and Excess Deaths

Being poor is associated with a greater risk of dying from various diseases and injuries. The table below shows relative risk (RR) and excess deaths for men and women in Canada.

Disease

RR (Men)

RR (Women)

Excess Deaths (%) Men

Excess Deaths (%) Women

Cardiovascular disease

1.67

1.53

19

18

Cancers

1.46

1.30

16

11

Diabetes

2.49

2.64

21

26

Respiratory disease

2.31

2.11

37

39

HIV/AIDS

3.14

3.11

18

30

Injuries

1.88

1.83

17

17

Greater risk of dying associated with being poor as compared to wealthy and excess deaths associated with income inequality for various diseases and injuries among Canadians

International Comparisons: Social Determinants and Health Outcomes

Finland, Canada, and US Rankings

Countries differ in their social determinants and health outcomes. Finland consistently ranks higher than Canada and the US in measures such as poverty, food security, income inequality, public expenditure, and child well-being.

Measure

Finland

Canada

US

% Living in poverty (2022)

3

18

34

Food security environment (2022)

1

7

34

Income inequality (2022)

7

14

36

Public expenditure (2022)

8

30

34

Life expectancy (2022)

15

18

31

Child well-being (2022)

5

19

37

Finland, Canada, and US Rankings on Selected Social Determinants of Health and Indicators of Population Health

Frameworks for Understanding Health Inequalities

Materialist Framework

The materialist framework emphasizes objective living conditions and socioeconomic position as predictors of health. Health gradients reflect stepwise differences, not just a rich-poor divide. Early life experiences, education, and employment shape future health and income potential.

Psychobiological Stress Response

Chronic stress leads to allostatic load, the cumulative wear and tear on the body. Dysfunctional stress responses can cause cardiovascular and immune system damage, accelerate aging, and increase risks for diabetes, heart disease, and premature death.

Lifecourse Perspective

Health outcomes are shaped across the life course by early exposures and accumulated conditions. Latent, pathway, and cumulative effects explain how disadvantage compounds over time.

Neo-Materialist Perspective

Health inequalities are shaped by how societies allocate resources. Universal health care, quality education, and strong public investment lead to better living conditions and fairer, healthier societies.

Social Comparison Perspective

Health inequalities arise not only from material deprivation but also from perceived social position. Feelings of shame, worthlessness, and envy activate stress pathways, leading to poorer physical and mental health.

Structural Inequities and Health

Gender, Race, Disability, and Immigration

Structural inequities concentrate disadvantage among certain groups. Women, racialized groups, immigrants, and people with disabilities face higher poverty, unemployment, and barriers to access, resulting in poorer health outcomes.

Best Practices for Scholarly Research

Effective Article Searching

  • Use Google Scholar with university access for peer-reviewed sources.

  • Filter results by year, relevance, and publication type.

  • Prefer sources with stable identifiers (DOI), credible authors, and recent publication dates.

  • Avoid non-academic sources such as blogs, social media, and opinion pieces.

Summary

Social determinants of health are central to understanding health inequalities. Material conditions, stress pathways, social comparisons, and structural inequities all contribute to health outcomes. International comparisons highlight the importance of policy and resource allocation in shaping population health.

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