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Multiple Choice
Increased water reabsorption in the descending limb of the nephron loop will result in which of the following?
A
Decreased water reabsorption in the collecting duct
B
A higher concentration of filtrate in the nephron loop
C
Increased sodium reabsorption in the descending limb
D
A lower concentration of filtrate in the nephron loop
Verified step by step guidance
1
Understand the anatomy and physiology of the nephron loop: The nephron loop (loop of Henle) consists of two limbs—descending and ascending. The descending limb is permeable to water but not to solutes, while the ascending limb is impermeable to water but actively transports sodium and chloride ions.
Analyze the function of the descending limb: Water reabsorption occurs in the descending limb due to the osmotic gradient in the renal medulla. As water leaves the filtrate, the concentration of solutes in the filtrate increases, resulting in a higher concentration of filtrate in the nephron loop.
Evaluate the options provided: Increased water reabsorption in the descending limb would not directly affect sodium reabsorption in the descending limb, as this limb is not involved in active solute transport. Similarly, it would not lead to decreased water reabsorption in the collecting duct, as water reabsorption in the collecting duct is regulated by antidiuretic hormone (ADH) and the osmotic gradient.
Focus on the correct answer: Increased water reabsorption in the descending limb leads to a higher concentration of filtrate in the nephron loop because water is removed, leaving solutes behind. This matches the correct answer provided in the problem.
Summarize the physiological mechanism: The descending limb's permeability to water and the osmotic gradient in the renal medulla are key factors in concentrating the filtrate. This process is essential for the kidney's ability to concentrate urine and maintain water balance in the body.