Here are the essential concepts you must grasp in order to answer the question correctly.
Centromere Function
The centromere is a specialized region of a chromosome that plays a crucial role during cell division. It is the point where sister chromatids are held together, ensuring proper segregation into daughter cells. This attachment is vital for maintaining genetic stability and preventing aneuploidy.
Recommended video:
Sister Chromatids
Sister chromatids are identical copies of a chromosome that are formed during DNA replication. They are joined at the centromere and are separated during mitosis or meiosis to ensure that each new cell receives an exact copy of the genetic material. Understanding their structure and behavior is essential for grasping the mechanics of cell division.
Recommended video:
Metaphase Alignment
During metaphase, chromosomes align at the cell's equatorial plane, facilitated by the spindle apparatus. This alignment is critical for ensuring that sister chromatids are evenly distributed to the daughter cells. The centromere's role in this process is to anchor the chromatids to the spindle fibers, allowing for accurate separation.
Recommended video: