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Multiple Choice
Which ions are necessary for both the intrinsic and extrinsic pathways of the coagulation cascade?
A
Calcium ions
B
Potassium ions
C
Sodium ions
D
Magnesium ions
Verified step by step guidance
1
Understand the coagulation cascade: The coagulation cascade is a series of events that lead to the formation of a blood clot. It consists of two pathways: intrinsic and extrinsic, which converge into a common pathway.
Identify the role of ions in the coagulation cascade: Ions play crucial roles in various physiological processes, including the coagulation cascade. They act as cofactors that are necessary for the activation of certain clotting factors.
Focus on calcium ions: Calcium ions (Ca2+) are essential for both the intrinsic and extrinsic pathways. They are required for the activation of several clotting factors, including factors IX and X, and for the conversion of prothrombin to thrombin.
Consider other ions: While calcium ions are necessary, other ions like potassium (K+), sodium (Na+), and magnesium (Mg2+) are not directly involved in the activation of the coagulation cascade pathways.
Conclude the necessity of calcium ions: Conclude that calcium ions are the key ions necessary for both the intrinsic and extrinsic pathways of the coagulation cascade, highlighting their importance in the clotting process.