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Multiple Choice
What is the primary function of cytotoxic T-cells in the immune system?
A
To directly kill infected host cells
B
To produce antibodies against pathogens
C
To activate B-cells to produce antibodies
D
To suppress the immune response to prevent autoimmunity
Verified step by step guidance
1
Understand the role of cytotoxic T-cells: Cytotoxic T-cells, also known as CD8+ T-cells, are a type of lymphocyte that play a crucial role in the immune system by directly attacking and destroying infected cells.
Identify the mechanism of action: Cytotoxic T-cells recognize infected cells through the presentation of foreign antigens on the surface of these cells, typically via Major Histocompatibility Complex (MHC) class I molecules.
Explore the process of cell destruction: Once a cytotoxic T-cell recognizes an infected cell, it releases perforin and granzymes. Perforin forms pores in the target cell membrane, allowing granzymes to enter and induce apoptosis (programmed cell death).
Differentiate from other immune functions: Unlike B-cells, which produce antibodies, cytotoxic T-cells do not produce antibodies. Their primary function is direct cell-mediated destruction of infected cells.
Clarify the role in immune regulation: Cytotoxic T-cells are not primarily involved in activating B-cells or suppressing the immune response. Their main function is to eliminate cells that have been compromised by pathogens, such as viruses.