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Multiple Choice
What is the result of preventing spindle fibers from forming during mitosis?
A
The nuclear envelope does not break down.
B
Cytokinesis occurs prematurely.
C
Chromosomes fail to align at the metaphase plate.
D
DNA replication is halted.
Verified step by step guidance
1
Understand the role of spindle fibers in mitosis: Spindle fibers are crucial for the movement and alignment of chromosomes during cell division. They form from the centrosomes and attach to the chromosomes at the centromeres.
Identify the stage of mitosis affected: Spindle fibers are primarily involved in the metaphase stage, where they help align chromosomes at the metaphase plate, ensuring each daughter cell receives the correct number of chromosomes.
Consider the consequences of spindle fiber disruption: Without spindle fibers, chromosomes cannot be properly aligned at the metaphase plate, leading to errors in chromosome segregation.
Evaluate the options given: Analyze each option to determine which one directly relates to the function of spindle fibers. The correct consequence of spindle fiber disruption is that chromosomes fail to align at the metaphase plate.
Conclude the impact on mitosis: Recognize that preventing spindle fiber formation disrupts the normal progression of mitosis, specifically affecting chromosome alignment and segregation, which can lead to cell division errors.