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Multiple Choice
Which of the following statements concerning the production of envelope proteins is true?
A
Envelope proteins are synthesized in the Golgi apparatus and then transported to the rough endoplasmic reticulum for packaging.
B
Envelope proteins are synthesized in the smooth endoplasmic reticulum and directly secreted out of the cell.
C
Envelope proteins are synthesized in the rough endoplasmic reticulum and then transported to the Golgi apparatus for further modification.
D
Envelope proteins are synthesized in the cytosol and then transported to the Golgi apparatus.
Verified step by step guidance
1
Understand the role of the rough endoplasmic reticulum (RER) in protein synthesis. The RER is studded with ribosomes, which are the sites of protein synthesis. Proteins destined for secretion or for use in the cell membrane are typically synthesized here.
Recognize the function of the Golgi apparatus in protein processing. After synthesis in the RER, proteins are transported to the Golgi apparatus, where they undergo further modifications, such as glycosylation, and are sorted for transport to their final destinations.
Consider the role of the smooth endoplasmic reticulum (SER). The SER is involved in lipid synthesis and detoxification processes, but it is not primarily responsible for the synthesis of proteins, especially envelope proteins.
Evaluate the statement about protein synthesis in the cytosol. While some proteins are synthesized in the cytosol, envelope proteins, which are typically membrane-bound, are synthesized in the RER to facilitate their integration into membranes.
Conclude that the correct statement is: 'Envelope proteins are synthesized in the rough endoplasmic reticulum and then transported to the Golgi apparatus for further modification.' This reflects the typical pathway for the synthesis and processing of membrane-bound and secretory proteins.