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Multiple Choice
At which site does the charged initiator tRNA bind during the initiation of protein synthesis?
A
P site
B
E site
C
A site
D
R site
Verified step by step guidance
1
Understand the process of initiation in protein synthesis, which involves the assembly of the ribosome, mRNA, and the initiator tRNA.
Recognize that the ribosome has three sites for tRNA binding: the A (aminoacyl), P (peptidyl), and E (exit) sites.
Identify the role of the initiator tRNA, which carries the first amino acid (usually methionine) and is crucial for starting the protein synthesis process.
Learn that during the initiation phase, the initiator tRNA binds to the P site of the ribosome, which is unique because normally new tRNAs enter at the A site.
Conclude that the charged initiator tRNA specifically binds to the P site to establish the correct reading frame for the mRNA and begin the translation process.