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Multiple Choice
In the process of translation, to which site on the ribosome does the initiator tRNA bind?
A
A site
B
T site
C
E site
D
P site
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Verified step by step guidance
1
Understand the process of translation, which is the synthesis of proteins from mRNA. It occurs in the ribosome, which has three sites for tRNA binding: A (aminoacyl), P (peptidyl), and E (exit).
Recognize that the initiator tRNA carries the first amino acid, methionine, and is crucial for starting the protein synthesis process.
Learn that during initiation, the small ribosomal subunit binds to the mRNA and the initiator tRNA binds to the start codon (AUG) on the mRNA.
Identify that the initiator tRNA binds to the P site of the ribosome. The P site holds the tRNA carrying the growing polypeptide chain, and the initiator tRNA starts this chain.
Note that after the initiator tRNA binds to the P site, the large ribosomal subunit joins to form a complete ribosome, allowing translation to proceed with the next tRNA entering the A site.