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Multiple Choice
Which of the following allows for ATP to be produced during the electron transport chain?
A
Oxidation of glucose in the cytoplasm
B
Direct transfer of electrons to ATP synthase
C
Conversion of pyruvate to acetyl-CoA
D
Proton gradient across the inner mitochondrial membrane
Verified step by step guidance
1
Understand the role of the electron transport chain (ETC) in cellular respiration. The ETC is the final stage of aerobic respiration, occurring in the inner mitochondrial membrane, where electrons are transferred through a series of complexes.
Recognize that the primary function of the ETC is to create a proton gradient across the inner mitochondrial membrane. As electrons move through the chain, protons (H⁺ ions) are pumped from the mitochondrial matrix into the intermembrane space.
Learn how the proton gradient is used to produce ATP. The accumulation of protons in the intermembrane space creates a high concentration gradient, which drives protons back into the matrix through ATP synthase, a process known as chemiosmosis.
Understand the role of ATP synthase. As protons flow back into the matrix through ATP synthase, the enzyme catalyzes the phosphorylation of ADP to ATP, utilizing the energy from the proton gradient.
Review why the other options are incorrect. Oxidation of glucose occurs in glycolysis, not directly in the ETC. Direct transfer of electrons to ATP synthase does not occur; ATP synthase uses the proton gradient. Conversion of pyruvate to acetyl-CoA happens before the Krebs cycle, not in the ETC.