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Multiple Choice
Which of the following pathogens undergoes antigenic variation to avoid immune defenses?
A
Streptococcus pneumoniae
B
Escherichia coli
C
Mycobacterium tuberculosis
D
Influenza virus
Verified step by step guidance
1
Understand the concept of antigenic variation: Antigenic variation is a mechanism used by certain pathogens to alter their surface proteins, allowing them to evade the host's immune system. This process helps the pathogen avoid detection and destruction by immune cells.
Identify pathogens known for antigenic variation: Some pathogens are well-known for their ability to undergo antigenic variation. These include viruses like the Influenza virus, which frequently changes its surface antigens, making it difficult for the immune system to recognize and respond effectively.
Consider the characteristics of each pathogen listed: Streptococcus pneumoniae, Escherichia coli, and Mycobacterium tuberculosis are bacteria, while the Influenza virus is a virus. Among these, the Influenza virus is renowned for its antigenic variation capabilities.
Review the immune evasion strategies of the Influenza virus: The Influenza virus undergoes frequent changes in its hemagglutinin and neuraminidase proteins, which are key antigens recognized by the immune system. This antigenic shift and drift are responsible for the virus's ability to cause seasonal flu outbreaks and pandemics.
Conclude with the identification of the correct pathogen: Based on the understanding of antigenic variation and the characteristics of the listed pathogens, the Influenza virus is the correct answer as it is known for undergoing antigenic variation to avoid immune defenses.