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Multiple Choice
Which viral receptor is involved in HIV attachment to the host cell?
A
MHC I
B
CXCR4
C
CCR5
D
CD4
Verified step by step guidance
1
Understand that HIV (Human Immunodeficiency Virus) targets specific cells in the human immune system, primarily CD4+ T cells.
Recognize that the initial step in HIV infection involves the virus attaching to the host cell. This attachment is mediated by specific receptors on the surface of the host cell.
Identify the primary receptor that HIV uses to attach to the host cell. In the case of HIV, the virus binds to the CD4 receptor on the surface of T cells.
Note that while CD4 is the primary receptor, HIV also requires co-receptors to successfully enter the host cell. These co-receptors are typically CCR5 or CXCR4, depending on the strain of the virus.
Conclude that the viral receptor involved in the initial attachment of HIV to the host cell is the CD4 receptor, which is crucial for the virus to gain entry into the cell.