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Multiple Choice
The mechanism for producing a concentrated urine involves all of the following except:
A
Secretion of antidiuretic hormone (ADH)
B
High permeability of the collecting duct to water
C
Increased glomerular filtration rate
D
Active transport of sodium in the ascending limb of the nephron loop
Verified step by step guidance
1
Step 1: Understand the mechanism of producing concentrated urine. Concentrated urine is formed when the body conserves water, primarily through the action of antidiuretic hormone (ADH), which increases water reabsorption in the collecting ducts.
Step 2: Review the role of ADH. ADH makes the collecting ducts highly permeable to water, allowing water to be reabsorbed into the bloodstream, thereby concentrating the urine.
Step 3: Examine the role of the nephron loop (loop of Henle). The ascending limb of the nephron loop actively transports sodium ions (Na+) out of the tubular fluid, creating a concentration gradient in the medulla that facilitates water reabsorption in the descending limb and collecting ducts.
Step 4: Analyze the impact of glomerular filtration rate (GFR). An increased GFR would result in a higher volume of filtrate entering the nephron, which could dilute the urine rather than concentrate it. This is why increased GFR is not part of the mechanism for producing concentrated urine.
Step 5: Conclude that the correct answer is 'Increased glomerular filtration rate,' as it does not contribute to the production of concentrated urine, unlike the other listed mechanisms.