Table of contents

1. Introduction to Anatomy & Physiology5h 43m
2. Cell Chemistry & Cell Components12h 36m
3. Energy & Cell Processes10h 6m
4. Tissues & Histology10h 3m
5. Integumentary System2h 20m
6. Bones & Skeletal Tissue2h 16m
7. The Skeletal System2h 35m
8. Joints2h 17m
9. Muscle Tissue2h 33m
10. Muscles1h 11m
11. Nervous Tissue and Nervous System1h 35m
12. The Central Nervous System1h 6m
- Introduction to the Central Nervous System
  18m
- The Cerebrum
  48m
13. The Peripheral Nervous System1h 26m
14. The Autonomic Nervous System1h 38m
15. The Special Senses2h 41m
16. The Endocrine System2h 48m
17. The Blood3h 22m
18. The Heart3h 42m
19. The Blood Vessels3h 35m
20. The Lymphatic System3h 16m
21. The Immune System14h 37m
22. The Respiratory System3h 20m
23. The Digestive System2h 5m
24. Metabolism and Nutrition4h 0m
25. The Urinary System2h 39m
26. Fluid and Electrolyte Balance, Acid Base Balance37m
27. The Reproductive System2h 5m
28. Human Development1h 21m
29. Heredity3h 32m

25. The Urinary System

Renal Physiology: Overview

Anatomy & Physiology

25. The Urinary System

Renal Physiology: Overview

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Multiple Choice

During the postoliguric phase of acute tubular necrosis, what is the primary effect on the renal tubules?

Progressive necrosis and irreversible loss of tubular structure

Initiation of glomerular filtration rate decline

Complete obstruction of the tubules by cellular debris

Regeneration of tubular epithelial cells and restoration of normal function

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Verified step by step guidance

Understand the phases of acute tubular necrosis (ATN): Acute tubular necrosis typically progresses through three phases—initiation, maintenance (oliguric phase), and recovery (postoliguric phase). The postoliguric phase is characterized by the recovery of renal function.

Recognize the primary effect during the postoliguric phase: During this phase, the renal tubules begin to regenerate. Tubular epithelial cells proliferate and repair damaged areas, restoring normal tubular structure and function.

Differentiate the postoliguric phase from other phases: Unlike the maintenance phase, which involves reduced glomerular filtration rate (GFR) and tubular obstruction, the postoliguric phase focuses on healing and functional recovery.

Understand the mechanism of regeneration: Tubular epithelial cells have the ability to undergo mitosis and replace damaged cells. This regeneration process is essential for restoring the kidney's ability to filter and reabsorb substances effectively.

Conclude the primary effect: The hallmark of the postoliguric phase is the regeneration of tubular epithelial cells and the restoration of normal renal function, distinguishing it from progressive necrosis or obstruction seen in earlier phases.