Table of contents

1. Introduction to Anatomy & Physiology5h 43m
2. Cell Chemistry & Cell Components12h 36m
3. Energy & Cell Processes10h 6m
4. Tissues & Histology10h 3m
5. Integumentary System2h 20m
6. Bones & Skeletal Tissue2h 16m
7. The Skeletal System2h 35m
8. Joints2h 17m
9. Muscle Tissue2h 33m
10. Muscles1h 11m
11. Nervous Tissue and Nervous System1h 35m
12. The Central Nervous System1h 6m
- Introduction to the Central Nervous System
  18m
- The Cerebrum
  48m
13. The Peripheral Nervous System1h 26m
14. The Autonomic Nervous System1h 38m
15. The Special Senses2h 41m
16. The Endocrine System2h 48m
17. The Blood3h 22m
18. The Heart3h 42m
19. The Blood Vessels3h 35m
20. The Lymphatic System3h 16m
21. The Immune System14h 37m
22. The Respiratory System3h 20m
23. The Digestive System2h 5m
24. Metabolism and Nutrition4h 0m
25. The Urinary System2h 39m
26. Fluid and Electrolyte Balance, Acid Base Balance37m
27. The Reproductive System2h 5m
28. Human Development1h 21m
29. Heredity3h 32m

21. The Immune System

Introduction to the Complement System

Anatomy & Physiology

21. The Immune System

Introduction to the Complement System

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Multiple Choice

In the lectin pathway of complement activation, what molecule is responsible for cleaving C4 and C2?

Properdin

Factor B

C1q

Mannose-binding lectin-associated serine protease (MASP)

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Verified step by step guidance

Understand the context: The lectin pathway is one of the pathways of the complement system, which is part of the immune response. It is activated by the binding of mannose-binding lectin (MBL) to carbohydrates on the surface of pathogens.

Identify the key components: In the lectin pathway, mannose-binding lectin (MBL) forms a complex with mannose-binding lectin-associated serine proteases (MASPs).

Determine the role of MASPs: MASPs are responsible for cleaving complement proteins C4 and C2, which are crucial steps in the activation of the complement cascade.

Differentiate from other molecules: Properdin and Factor B are involved in the alternative pathway, while C1q is part of the classical pathway. These molecules do not play a role in cleaving C4 and C2 in the lectin pathway.

Conclude with the correct molecule: The molecule responsible for cleaving C4 and C2 in the lectin pathway is the Mannose-binding lectin-associated serine protease (MASP).