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Multiple Choice
Which of the following statements about the complement system is incorrect?
A
The complement system is part of the innate immune response.
B
The complement system is activated only by antibodies.
C
The complement system can directly kill pathogens by forming a membrane attack complex.
D
Complement proteins are primarily produced by the liver.
Verified step by step guidance
1
Understand the role of the complement system: The complement system is a part of the innate immune response, which means it acts as a first line of defense against pathogens.
Identify the activation mechanisms: The complement system can be activated through several pathways, including the classical pathway (which involves antibodies), the alternative pathway, and the lectin pathway. Therefore, it is not activated only by antibodies.
Explore the function of the complement system: One of the key functions of the complement system is to directly kill pathogens by forming a membrane attack complex (MAC), which creates pores in the pathogen's membrane, leading to cell lysis.
Recognize the source of complement proteins: Complement proteins are primarily produced by the liver, which is responsible for synthesizing many components of the immune system.
Evaluate the statements: Based on the understanding of the complement system, identify the incorrect statement. The statement 'The complement system is activated only by antibodies' is incorrect because the system can be activated by multiple pathways, not solely by antibodies.