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Multiple Choice
Which protein is a thick filament involved in muscle contractions and contains heads that form cross-bridges?
A
Myosin
B
Actin
C
Troponin
D
Tropomyosin
Verified step by step guidance
1
Begin by understanding the structure of muscle fibers, which are composed of myofibrils. Myofibrils contain repeating units called sarcomeres, the basic functional units of muscle contraction.
Identify the two main types of filaments within the sarcomere: thick filaments and thin filaments. Thick filaments are primarily composed of the protein myosin, while thin filaments are primarily composed of actin, along with regulatory proteins troponin and tropomyosin.
Focus on the role of myosin in muscle contraction. Myosin is a motor protein that forms the thick filaments. It has a tail and two heads, which are crucial for its function in muscle contraction.
Understand the mechanism of muscle contraction. Myosin heads bind to actin filaments to form cross-bridges. This interaction is essential for the sliding filament model of muscle contraction, where the myosin heads pull the actin filaments, causing the sarcomere to shorten and generate force.
Recognize the importance of cross-bridge formation. The myosin heads undergo a cycle of attachment, pivoting, detachment, and reattachment to actin, powered by ATP hydrolysis, which leads to muscle contraction.