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Multiple Choice
Which of the following induces a type III hypersensitivity reaction?
A
Delayed-type hypersensitivity
B
IgE-mediated response
C
Cytotoxic T cell activation
D
Immune complex formation
Verified step by step guidance
1
Understand the concept of hypersensitivity reactions: Hypersensitivity reactions are exaggerated immune responses that can cause tissue damage. They are classified into four types: Type I, Type II, Type III, and Type IV.
Identify the characteristics of Type III hypersensitivity: Type III hypersensitivity is characterized by the formation of immune complexes, which are aggregates of antigens and antibodies. These complexes can deposit in tissues and lead to inflammation and tissue damage.
Differentiate between the types of hypersensitivity: Type I is IgE-mediated and involves allergic reactions. Type II involves cytotoxic reactions mediated by antibodies. Type IV is delayed-type hypersensitivity involving T cell activation.
Recognize the role of immune complexes in Type III hypersensitivity: In Type III hypersensitivity, the immune complexes formed can activate the complement system, leading to inflammation and recruitment of immune cells to the site of deposition.
Conclude that immune complex formation is the mechanism behind Type III hypersensitivity: Based on the characteristics and mechanisms involved, immune complex formation is the correct answer for inducing a Type III hypersensitivity reaction.