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Multiple Choice
Where is the first amino acid in a polypeptide chain located?
A
At the N-terminus
B
At the C-terminus
C
In the middle of the chain
D
At the carboxyl end
Verified step by step guidance
1
Understand the structure of a polypeptide chain: A polypeptide is a linear sequence of amino acids linked by peptide bonds.
Identify the ends of a polypeptide chain: The two ends are the N-terminus and the C-terminus. The N-terminus has a free amino group (-NH2), while the C-terminus has a free carboxyl group (-COOH).
Recognize the direction of synthesis: Polypeptides are synthesized from the N-terminus to the C-terminus during translation.
Determine the location of the first amino acid: The first amino acid in a polypeptide chain is located at the N-terminus, where the synthesis begins.
Clarify the options: The N-terminus is where the first amino acid is located, not at the C-terminus, in the middle, or at the carboxyl end.