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Multiple Choice
Which of the following bone cell types is primarily responsible for initiating ossification of bone?
A
Osteocytes
B
Osteoclasts
C
Osteoblasts
D
Chondrocytes
Verified step by step guidance
1
Understand the role of each bone cell type: Osteocytes are mature bone cells that maintain the bone matrix. Osteoclasts are responsible for bone resorption, breaking down bone tissue. Chondrocytes are involved in cartilage formation, not directly in bone ossification.
Focus on osteoblasts: These cells are primarily responsible for bone formation. They synthesize and secrete the bone matrix and initiate the process of ossification.
Ossification is the process of bone tissue formation. It begins with osteoblasts laying down the organic components of the bone matrix, primarily collagen.
Osteoblasts also facilitate the mineralization of the bone matrix by depositing calcium and phosphate, which hardens the matrix and completes the ossification process.
Recognize that osteoblasts are crucial for bone growth and repair, as they are the cells that initiate and drive the ossification process.