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Multiple Choice
What is the primary functional difference between the smooth and rough endoplasmic reticulum (ER) in the context of protein secretion?
A
The smooth ER is responsible for protein folding, while the rough ER is responsible for protein degradation.
B
The smooth ER stores calcium ions, while the rough ER synthesizes carbohydrates.
C
The smooth ER is involved in lipid synthesis, while the rough ER is involved in protein synthesis.
D
The smooth ER modifies proteins, while the rough ER transports proteins to the Golgi apparatus.
Verified step by step guidance
1
Understand the structure of the endoplasmic reticulum (ER): The ER is a network of membranes within the cell, and it comes in two forms - smooth and rough.
Identify the rough ER: The rough ER is studded with ribosomes on its surface, which gives it a 'rough' appearance under a microscope. These ribosomes are the sites of protein synthesis.
Identify the smooth ER: The smooth ER lacks ribosomes, giving it a 'smooth' appearance. It is involved in various metabolic processes, including lipid synthesis and detoxification.
Differentiate the functions: The rough ER is primarily involved in the synthesis of proteins that are either secreted from the cell, incorporated into the cell's plasma membrane, or sent to an organelle. The smooth ER, on the other hand, is involved in the synthesis of lipids, metabolism of carbohydrates, and storage of calcium ions.
Relate to protein secretion: In the context of protein secretion, the rough ER plays a crucial role as it synthesizes proteins that are destined for secretion. These proteins are then transported to the Golgi apparatus for further processing and eventual secretion out of the cell.