Join thousands of students who trust us to help them ace their exams!Watch the first video
Multiple Choice
Which of the following substances can pass through a gap junction?
A
DNA
B
Ions
C
Lipids
D
Proteins
Verified step by step guidance
1
Understand the structure and function of gap junctions: Gap junctions are specialized intercellular connections that allow for direct communication between cells. They are composed of connexin proteins that form channels, permitting the passage of certain small molecules and ions between adjacent cells.
Identify the types of substances that can pass through gap junctions: Gap junctions typically allow the passage of small molecules and ions, such as calcium ions (Ca²⁺), potassium ions (K⁺), and other small signaling molecules. These channels are not large enough to allow the passage of larger molecules like proteins or nucleic acids.
Evaluate the size and charge of the substances listed: DNA and proteins are large macromolecules, while lipids are generally nonpolar and larger than ions. Ions, on the other hand, are small and charged, making them suitable for passage through the narrow channels of gap junctions.
Consider the physiological role of gap junctions: Gap junctions are crucial for cell-to-cell communication, particularly in tissues that require rapid and coordinated responses, such as cardiac and smooth muscle tissues. The passage of ions through gap junctions facilitates the propagation of electrical signals necessary for synchronized contraction.
Conclude which substance can pass through gap junctions: Based on the size and nature of the substances, ions are the most likely candidates to pass through gap junctions, as they are small enough to fit through the channels and are essential for cellular communication.