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Multiple Choice
How do conditions around metabolically active tissues affect the oxyhemoglobin dissociation curve?
A
Shift the curve to the right
B
Have no effect on the curve
C
Shift the curve to the left
D
Cause the curve to become linear
Verified step by step guidance
1
Understand the oxyhemoglobin dissociation curve: This curve represents the relationship between the partial pressure of oxygen (pO2) and the saturation of hemoglobin with oxygen. It is typically sigmoidal in shape.
Identify factors affecting the curve: Metabolically active tissues produce more carbon dioxide, increase temperature, and lower pH due to increased metabolic activity. These factors influence the curve.
Consider the Bohr effect: The Bohr effect describes how increased carbon dioxide and decreased pH (more acidic conditions) lead to hemoglobin releasing oxygen more readily, causing a rightward shift in the curve.
Analyze the impact of temperature: Higher temperatures, often found in metabolically active tissues, also cause hemoglobin to release oxygen more easily, contributing to a rightward shift in the curve.
Conclude the effect on the curve: Given the conditions around metabolically active tissues (increased CO2, lower pH, higher temperature), the oxyhemoglobin dissociation curve shifts to the right, facilitating oxygen release to tissues.