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Multiple Choice
Which molecule on the thin filament has a binding site for calcium?
A
Actin
B
Myosin
C
Troponin
D
Tropomyosin
Verified step by step guidance
1
Step 1: Begin by identifying the components of the thin filament in muscle fibers. The thin filament is primarily composed of actin, tropomyosin, and troponin.
Step 2: Understand the role of calcium in muscle contraction. Calcium ions bind to specific molecules on the thin filament to initiate the contraction process.
Step 3: Learn the function of troponin. Troponin is a regulatory protein complex that has three subunits: Troponin C (binds calcium), Troponin I (inhibits actin-myosin interaction), and Troponin T (binds tropomyosin).
Step 4: Recognize that Troponin C is the subunit responsible for binding calcium ions during muscle contraction. This binding causes a conformational change in the troponin-tropomyosin complex, exposing the binding sites on actin for myosin.
Step 5: Confirm that actin, myosin, and tropomyosin do not directly bind calcium. Actin is the structural protein, myosin is the motor protein, and tropomyosin regulates access to actin's binding sites. Troponin is the correct molecule with a binding site for calcium.