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Multiple Choice
The filtration membrane includes all of the following except:
A
Juxtaglomerular cells
B
Basement membrane
C
Fenestrated endothelium
D
Podocyte filtration slits
Verified step by step guidance
1
Step 1: Begin by understanding the filtration membrane, which is a structure in the kidney responsible for filtering blood in the glomerulus. It consists of three main components: the fenestrated endothelium, the basement membrane, and the podocyte filtration slits.
Step 2: Review the function of each component of the filtration membrane. The fenestrated endothelium allows the passage of water and small solutes while blocking larger molecules. The basement membrane acts as a selective barrier, preventing the passage of large proteins. The podocyte filtration slits further refine the filtration process by blocking medium-sized molecules.
Step 3: Examine the role of juxtaglomerular cells. These cells are not part of the filtration membrane; instead, they are involved in regulating blood pressure and the release of renin. This distinction is key to identifying the correct answer.
Step 4: Compare the listed options to the components of the filtration membrane. Juxtaglomerular cells are not involved in the filtration process, whereas the basement membrane, fenestrated endothelium, and podocyte filtration slits are integral parts of the filtration membrane.
Step 5: Conclude that the correct answer is 'Juxtaglomerular cells,' as they are not part of the filtration membrane but are involved in regulatory functions outside of filtration.