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Multiple Choice
Which of the following best describes tight junctions?
A
They anchor cells to the extracellular matrix.
B
They facilitate communication between cells through direct cytoplasmic connections.
C
They allow the passage of ions and small molecules between cells.
D
They create a watertight seal between adjacent cells.
Verified step by step guidance
1
Understand the function of tight junctions: Tight junctions are specialized connections between adjacent cells that create a watertight seal, preventing the passage of substances between the cells.
Differentiate tight junctions from other types of cell junctions: Unlike anchoring junctions, which attach cells to the extracellular matrix, or gap junctions, which allow communication through cytoplasmic connections, tight junctions focus on sealing spaces between cells.
Consider the physiological role of tight junctions: They are crucial in tissues where a barrier is needed, such as in the epithelial lining of organs, to prevent leakage of materials between cells.
Visualize the structure: Tight junctions are formed by a network of claudins and occludins, proteins that interlock to form a continuous seal around the cell perimeter.
Apply this understanding to the options given: Recognize that the option describing tight junctions as creating a watertight seal between adjacent cells is the most accurate description of their function.