Question 1

Which of the following structures is responsible for the production of male gametes and secretion of androgens?

Accepted Answer

Testes

Question 2

A patient presents with a low sperm count and abnormally low semen volume. Which accessory gland is most likely malfunctioning?

Accepted Answer

Seminal gland

Question 3

Which muscle is responsible for wrinkling the scrotal surface and assisting in temperature regulation of the testes?

Accepted Answer

Dartos muscle

Question 4

During spermatogenesis, which cell type is the first to enter meiosis?

Accepted Answer

Primary spermatocyte

Question 5

Which of the following best describes the function of the blood-testis barrier?

Accepted Answer

It isolates seminiferous tubules from general circulation.

Question 6

A male patient has a mutation that prevents the secretion of inhibin. What is the most likely consequence?

Accepted Answer

Increased secretion of FSH

Question 7

Which hormone directly stimulates the interstitial endocrine cells (Leydig cells) to produce testosterone?

Accepted Answer

Luteinizing hormone (LH)

Question 8

Which of the following is a correct sequence of events in spermatogenesis?

Accepted Answer

Spermatogonium → Primary spermatocyte → Secondary spermatocyte → Spermatid → Sperm

Question 9

Which component of semen is responsible for forming a temporary clot in the vagina after ejaculation?

Accepted Answer

Fibrinogen

Question 10

A 35-year-old male is found to have sperm that are mature but immobile upon leaving the epididymis. Which process must these sperm undergo to become motile and capable of fertilization?

Accepted Answer

Capacitation

Question 11

Which of the following best explains why the testes are located outside the body cavity in the scrotum?

Accepted Answer

To maintain a temperature about 1.1ºC lower than body temperature for optimal sperm development

Question 12

Which of the following is NOT a function of nurse (Sertoli) cells?

Accepted Answer

Secretion of testosterone

Question 13

A patient with a deficiency in the enzyme aromatase would most likely have decreased levels of which hormone in the plasma?

Accepted Answer

Estradiol

Question 14

Which of the following best describes the chromosomal content of secondary spermatocytes produced during spermatogenesis?

Accepted Answer

23 chromosomes, each with a pair of duplicate chromatids

Question 15

Which hormone is released in pulses every 60–90 minutes and regulates the secretion of FSH and LH?

Accepted Answer

Gonadotropin-releasing hormone (GnRH)

Question 16

A male patient has a genetic mutation that prevents the formation of tight junctions between nurse cells. Which process would be most directly affected?

Accepted Answer

Maintenance of the blood-testis barrier

Question 17

Which of the following is a function of the bulbo-urethral glands?

Accepted Answer

Secretion of thick, alkaline mucus to neutralize urinary acids

Question 18

Which of the following best describes the role of androgen-binding protein (ABP) in the seminiferous tubules?

Accepted Answer

It binds testosterone, increasing its concentration and stimulating spermiogenesis.

Question 19

Which of the following is a direct effect of testosterone on the male body?

Accepted Answer

Stimulation of spermatogenesis

Question 20

Which of the following best explains why sperm must absorb nutrients from the surrounding fluid rather than synthesizing them internally?

Accepted Answer

Sperm lack endoplasmic reticulum, Golgi apparatus, lysosomes, and peroxisomes

The Male Reproductive System: Structure, Function, and Spermatogenesis

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