Table of contents

1. Introduction to Biochemistry4h 34m
2. Water3h 23m
3. Amino Acids8h 10m
4. Protein Structure10h 4m
5. Protein Techniques14h 5m
6. Enzymes and Enzyme Kinetics13h 38m
7. Enzyme Inhibition and Regulation 8h 42m
8. Protein Function 9h 41m
9. Carbohydrates7h 49m
10. Lipids5h 49m
11. Biological Membranes and Transport 6h 37m
12. Biosignaling9h 45m
Review 1: Nucleic Acids, Lipids, & Membranes2h 47m
Review 2: Biosignaling, Glycolysis, Gluconeogenesis, & PP-Pathway3h 12m
Review 3: Pyruvate & Fatty Acid Oxidation, Citric Acid Cycle, & Glycogen Metabolism2h 26m
Review 4: Amino Acid Oxidation, Oxidative Phosphorylation, & Photophosphorylation1h 48m

6. Enzymes and Enzyme Kinetics

Enzymes

Biochemistry

6. Enzymes and Enzyme Kinetics

Enzymes

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Multiple Choice

Which enzyme is primarily responsible for hydrolyzing triglycerides in chylomicrons, allowing their uptake into cells?

Hormone-sensitive lipase

Acetyl-CoA carboxylase

Pancreatic lipase

Lipoprotein lipase

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Verified step by step guidance

Understand the role of chylomicrons: Chylomicrons are lipoprotein particles that transport dietary triglycerides and cholesterol from the intestines to tissues. To allow uptake into cells, triglycerides must be hydrolyzed into free fatty acids and glycerol.

Identify the enzyme responsible for hydrolyzing triglycerides in chylomicrons: Lipoprotein lipase (LPL) is the enzyme that catalyzes this reaction. It is located on the endothelial surface of capillaries in tissues such as adipose tissue and muscle.

Clarify the mechanism of action: Lipoprotein lipase hydrolyzes the ester bonds in triglycerides, breaking them down into free fatty acids and glycerol. These products can then be absorbed by nearby cells for energy production or storage.

Differentiate lipoprotein lipase from other enzymes: Hormone-sensitive lipase is involved in mobilizing stored fat from adipose tissue, not hydrolyzing triglycerides in chylomicrons. Acetyl-CoA carboxylase is involved in fatty acid synthesis, and pancreatic lipase acts in the digestive system to break down dietary fats in the intestine.

Conclude the importance of lipoprotein lipase: Lipoprotein lipase is essential for lipid metabolism and energy homeostasis, as it facilitates the delivery of fatty acids to tissues for storage or energy use.